Simple and non-charged long-lived fluorescent intracellular organelle trackers

Herrero-Foncubierta, Pilar; González García, María del Carmen; Resa, Sandra; Paredes Martínez, José Manuel; Ripoll, Consuelo; Girón González, María Dolores; Salto González, Rafael; Cuerva Carvajal, Juan Manuel; Orte Gutiérrez, Ángel; Miguel Álvarez, Delia

doi:10.1016/j.dyepig.2020.108649

Preprint (438.2Ko)

Identificadores

URI: http://hdl.handle.net/10481/73011

DOI: 10.1016/j.dyepig.2020.108649

Exportar

Editorial

Elsevier

Materia

FLIM

Organelle polarity maps

Fluorescent probes

Long-lived dyes

Mitochondria targeting

Date

2020-12

Referencia bibliográfica

Pilar Herrero-Foncubierta, María del Carmen González-García, Sandra Resa, Jose Manuel Paredes, Consuelo Ripoll, Maria D. Girón, Rafael Salto, Juan M. Cuerva, Angel Orte, Delia Miguel, Simple and non-charged long-lived fluorescent intracellular organelle trackers, Dyes and Pigments (2020) https://doi.org/10.1016/j.dyepig.2020.108649.

Patrocinador

Ministerio de Economía y Competitividad for funding (CTQ2017-85454-C2-1-P and CTQ2017-85658-R).; Junta de Andalucía; Ministerio de Economía y Competitividad

Résumé

In this work we evaluated by FLIM microscopy the preferential accumulation of long-lived acridone derivatives in mitochondria and lysosomes, based on a new concept of non-protonable and non-charged groups carriers. Thus, thiophene ring has been proved to act as mithocondria carrier whereas pyridine derivative is preferentially accumulated into lisosomes.

Colecciones

FQM 247 - Artículos

Excepté là où spécifié autrement, la license de ce document est décrite en tant que Atribución-NoComercial-SinDerivadas 3.0 España