|dc.description.abstract||PURPOSE: The purpose of the study was to study the relationship between pseudoexfoliation (PES) and other
predictors in the development of complications in cataract surgery by phacoemulsification in patients with PES.
METHODS: A retrospective cohort study of patients undergoing cataract surgery by phacoemulsification in the
health area of Cee in northwestern Spain during the 2‑year period from 2009 to 2010. Capsule rupture, choroidal
hemorrhage, and vitreous loss were included as complications and intraoperative nucleus or lens dislocation as
the independent variable. PES, age, hardness, type of cataract, myopia, preoperative visual acuity, antiplatelet
use, anticoagulant uses, alpha agonist use, mydriasis prior to surgery, anterior chamber depth, and axial length
were included as predictor variables. All predictive hierarchical models were tested using as a selection criterion
the one minimizing the Akaike index.
RESULTS: A total of 551 patients were initially identified from hospital register, of which 48 were excluded due
to the presence of an exclusion factor. After the initial selection, the final sample was 681 eyes of 503 patients.
Of the 8192 possible models, a model with the following seven variables was selected: PES, steroid use, alpha
agonist use, nuclear hardness, mydriasis, anterior chamber depth, and axial length. The selected model had
an Akaike index of 435.4 and an area under the curve of 0.7895 corresponding to a sensitivity of 6.2% and a
specificity of 98.5%.
CONCLUSION: PES, nuclear hardness, and alpha agonist use are risk factors strongly predictive of