Implications of Vitamins in COVID-19 Prevention and Treatment through Immunomodulatory and Anti-Oxidative Mechanisms
Metadatos
Mostrar el registro completo del ítemAutor
Toledano, Juan M.; Moreno Fernández, Jorge; Puche Juárez, María; Ochoa Herrera, Julio José; Díaz Castro, JavierEditorial
MDPI
Materia
Vitamins SARS-CoV-2 COVID-19 Nutrients Immunity Inflammation Oxidative stress
Fecha
2021-12-21Referencia bibliográfica
Toledano, J.M... [et al.]. Implications of Vitamins in COVID-19 Prevention and Treatment through Immunomodulatory and Anti-Oxidative Mechanisms. Antioxidants 2022, 11, 5. [https://doi.org/10.3390/antiox11010005]
Patrocinador
Vicerrectorado de Investigacion y Transferencia of University of Granada, "Programa de Estimulacion a la Investigacion"Resumen
Since the appearance of the coronavirus disease 2019 (COVID-19) and its announcement as
a global pandemic, the search for prophylactic and therapeutic options have become a priority for
governments and the scientific community. The approval of several vaccines against SARS-CoV-2 is
being crucial to overcome this situation, although the victory will not be achieved while the whole
population worldwide is not protected against the virus. This is why alternatives should be studied
in order to successfully support the immune system before and during a possible infection. An
optimal inflammatory and oxidative stress status depends on an adequate diet. Poor levels of several
nutrients could be related to an impaired immune response and, therefore, an increased susceptibility
to infection and serious outcomes. Vitamins exert a number of anti-microbial, immunomodulatory,
anti-inflammatory, and antioxidant activities, which can be of use to fight against this and several
other diseases (especially vitamin D and C). Even though they cannot be considered as a definitive
therapeutic option, in part owing to the lack of solid conclusions from well-designed clinical trials,
currently available evidence from similar respiratory diseases may indicate that it would be rational
to deeply explore the use of vitamins during this global pandemic.