dc.contributor.author | Roldán Nofuentes, José Antonio | |
dc.contributor.author | Bouh Regad, Saad | |
dc.date.accessioned | 2021-11-09T07:40:07Z | |
dc.date.available | 2021-11-09T07:40:07Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Roldán‐Nofuentes, J.A.; Regad, S.B. Comparison of the Average Kappa Coefficients of Two Binary Diagnostic Tests with Missing Data. Mathematics 2021, 9, 2834. https://doi.org/10.3390/ math9212834 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10481/71377 | |
dc.description.abstract | The average kappa coefficient of a binary diagnostic test is a parameter that measures the
average beyond‐chance agreement between the diagnostic test and the gold standard. This
parameter depends on the accuracy of the diagnostic test and also on the disease prevalence. This
article studies the comparison of the average kappa coefficients of two binary diagnostic tests when
the gold standard is not applied to all individuals in a random sample. In this situation, known as
partial disease verification, the disease status of some individuals is a missing piece of data.
Assuming that the missing data mechanism is missing at random, the comparison of the average
kappa coefficients is solved by applying two computational methods: the EM algorithm and the
SEM algorithm. With the EM algorithm the parameters are estimated and with the SEM algorithm
their variances‐covariances are estimated. Simulation experiments have been carried out to study
the sizes and powers of the hypothesis tests studied, obtaining that the proposed method has good
asymptotic behavior. A function has been written in R to solve the proposed problem, and the
results obtained have been applied to the diagnosis of Alzheimerʹs disease. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | Atribución 3.0 España | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.subject | EM algorithm | es_ES |
dc.subject | Partial verification | es_ES |
dc.subject | SEM algorithm | es_ES |
dc.title | Comparison of the Average Kappa Coefficients of Two Binary Diagnostic Tests with Missing Data | es_ES |
dc.type | journal article | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.identifier.doi | 10.3390/math9212834 | |