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dc.contributor.authorDe Porras Carrique, Teresa
dc.contributor.authorGonzález Moles, Miguel Ángel 
dc.contributor.authorRamos García, Pablo
dc.identifier.citationDe Porras-Carrique, T... [et al.]. Depression, anxiety, and stress in oral lichen planus: a systematic review and meta-analysis. Clin Oral Invest (2021). []es_ES
dc.descriptionUniversidad de Granada/CBUAes_ES
dc.description.abstractObjectives We present this systematic review and meta-analyses to evaluate current evidence on the prevalence of depression, anxiety, and stress in patients with oral lichen planus and their magnitude of association. Material and methods We searched PubMed, Embase, Web of Science, Scopus, PsycInfo, and Google Scholar for studies published before January 2021. We evaluated the quality of studies using a specific method for systematic reviews addressing prevalence questions, designed by the Joanna Briggs Institute. We carried out meta-analyses and performed heterogeneity, subgroups, meta-regression, and small-study effects analyses. Results Fifty-one studies (which recruited 6,815 patients) met the inclusion criteria. Our results reveal a high prevalence of depression (31.19%), anxiety (54.76%), and stress (41.10%) in oral lichen planus. Furthermore, OLP patients presented a significantly higher relative frequency than control group without OLP for depression (OR = 6.15, 95% CI = 2.73–13.89, p < 0.001), anxiety (OR = 3.51, 95% CI = 2.10–5.85, p < 0.001), and stress (OR = 3.64, 95% CI = 1.48–8.94, p = 0.005), showing large effect sizes. Subgroups meta-analyses showed the relevance of the participation of psychologists and psychiatrists in the diagnosis of depression, anxiety, and stress in patients with OLP. Multivariable meta-regression analysis showed the importance of the comorbidity of depression-anxiety in patients with OLP. Conclusions Our systematic review and meta-analysis show that patients with OLP suffer a higher prevalence of depression, anxiety, and stress, being more frequent than in general population. Clinical relevance In the dental clinic, especially dentists should be aware of depression, anxiety, and stress in OLP patients to achieve a correct referral.es_ES
dc.description.sponsorshipUniversidad de Granada/CBUAes_ES
dc.rightsAtribución 3.0 España*
dc.subjectOral lichen planuses_ES
dc.subjectAnxiety es_ES
dc.subjectStress es_ES
dc.subjectSystematic reviewes_ES
dc.titleDepression, anxiety, and stress in oral lichen planus: a systematic review and meta‑analysises_ES

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Atribución 3.0 España
Except where otherwise noted, this item's license is described as Atribución 3.0 España