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dc.contributor.authorPapantoniou, Kyriaki
dc.contributor.authorJiménez Moleón, José Juan 
dc.contributor.authorOlmedo Requena, María Rocío 
dc.date.accessioned2021-07-01T11:24:12Z
dc.date.available2021-07-01T11:24:12Z
dc.date.issued2021-06-03
dc.identifier.citationPapantoniou, K., Castaño-Vinyals, G., Espinosa, A. et al. Sleep duration and napping in relation to colorectal and gastric cancer in the MCC-Spain study. Sci Rep 11, 11822 (2021). [https://doi.org/10.1038/s41598-021-91275-3]es_ES
dc.identifier.urihttp://hdl.handle.net/10481/69459
dc.description.abstractSleep duration is a novel and potentially modifiable risk factor for cancer. We evaluated the association of self-reported sleep duration and daytime napping with odds of colorectal and gastric cancer. We included 2008 incident colorectal cancer cases, 542 gastric cancer cases and 3622 frequency-matched population controls, recruited in the MCC-Spain case–control study (2008–2013). Sleep information, socio-demographic and lifestyle characteristics were obtained through personal interviews. Multivariable adjusted logistic regression models were used to estimate odds ratios (OR) with 95% confidence intervals (CI) for cancer, across categories of sleep duration (≤ 5, 6, 7, 8, ≥ 9 hours/day), daytime napping frequency (naps/week) and duration (minutes/nap). Compared to 7 hours of sleep, long sleep was associated with increased odds of colorectal ( OR≥9 hours: 1.59; 95%CI 1.30–1.94) and gastric cancer ( OR≥9 hours: 1.95; 1.37–2.76); short sleep was associated with increased odds of gastric cancer ( OR≤5 hours: 1.32; 0.93–1.88). Frequent and long daytime naps increased the odds of colorectal ( OR6–7 naps/week, ≥30 min: 1.32; 1.14–1.54) and gastric cancer ( OR6–7 naps/week, ≥30 min: 1.56; 1.21–2.02). Effects of short sleep and frequent long naps were stronger among participants with night shift-work history. Sleep and circadian disruption may jointly play a role in the etiology of colorectal and gastric cancer.es_ES
dc.description.sponsorshipCatalan Government DURSI 2009SGR1489,RYC-2017-01892es_ES
dc.description.sponsorshipCatalan Institute of Oncologyes_ES
dc.description.sponsorshipCentro de Investigacion Biomedica en Red: Epidemiologia y Salud Publicaes_ES
dc.description.sponsorshipConsejería de Salud of the Junta de Andalucía 2009-S0143es_ES
dc.description.sponsorshipFEDER funds/European Regional Develpment Fundes_ES
dc.description.sponsorshipICGC International Cancer Genome Consortium CLLes_ES
dc.description.sponsorshipICOBIOBANCes_ES
dc.description.sponsorshipRed Temática de Investigación del Cáncer RD12/0036/0036es_ES
dc.description.sponsorshipSpanish Association Against Canceres_ES
dc.description.sponsorshipXarxa de Bancs de Tumors de Cata-lunyaes_ES
dc.description.sponsorshipAlbert Einstein Cancer Center AECCes_ES
dc.description.sponsorshipMinisterio de Ciencia, Innovación y Universidades MCIUes_ES
dc.description.sponsorshipEno Scientific Foundationes_ES
dc.description.sponsorshipEuropean Commission FOOD-CT-2006-036224-HIWATE ECes_ES
dc.description.sponsorshipGeneralitat de Catalunya 2017SGR723es_ES
dc.description.sponsorshipAgència de Gestió d'Ajuts Universitaris i de Recerca 2017SGR1085 AGAURes_ES
dc.description.sponsorshipMinisterio de Economía y Competitividad MINECOes_ES
dc.description.sponsorshipInstituto de Salud Carlos III PI08/0533,PI08/1359,PI08/1770,PI11/00226,PI11/01403,PI11/01810,PI11/02213,PI12/00150,PI12/00265,PI12/00488,PI12/00715,PI12/01270 ISCIIIes_ES
dc.description.sponsorshipMinisterio de Ciencia e Innovación CEX2018-000806-S MICINNes_ES
dc.description.sponsorshipEuropean Social Fund ESFes_ES
dc.description.sponsorshipEuropean Regional Development Fund PI17/01280 ERDFes_ES
dc.description.sponsorshipConselleria de Sanitat Universal i Salut Pública 2010ACUP 00310,AP_061/10es_ES
dc.description.sponsorshipJunta de Castilla y León LE22A10-2es_ES
dc.description.sponsorshipFundación Marqués de Valdecilla API 10/09 FMVes_ES
dc.language.isoenges_ES
dc.publisherSpringer Naturees_ES
dc.rightsAtribución 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.titleSleep duration and napping in relation to colorectal and gastric cancer in the MCC‑Spain studyes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.1038/s41598-021-91275-3
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones_ES


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