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dc.contributor.authorQuiñones Vico, María Isabel 
dc.contributor.authorSanabria de la Torre, Raquel 
dc.contributor.authorSánchez Diaz, Manuel
dc.contributor.authorSierra Sánchez, Álvaro
dc.contributor.authorMontero Vilchez, Trinidad
dc.contributor.authorFernández González, Ana
dc.contributor.authorArias Santiago, Salvador Antonio
dc.identifier.citationQuiñones-Vico MI, Sanabria-de la Torre R, Sánchez-Díaz M, Sierra-Sánchez Á, Montero-Vílchez T, Fernández-González A and Arias-Santiago S (2021) The Role of Exosomes Derived From Mesenchymal Stromal Cells in Dermatology. Front. Cell Dev. Biol. 9:647012. doi: [10.3389/fcell.2021.647012]es_ES
dc.descriptionThis study has been funded by the Carlos III Health Institute of Spain through the PI13/02576 and PI17/02083 projects [cofunded by European Regional Development Fund "A way to make Europe" and Andalusian Regional Government Finance (SAS PI-0458-2016)]. The work of MQ-V was supported by a predoctoral fellowship (BOE 22/10/2019) from the Spanish Ministry of Science, Innovation and Universities. This study is part of her doctoral research in the Biomedicine program at the University of Granada.es_ES
dc.description.abstractThe skin is the largest organ of the human body and its main functions include providing protection from external harmful agents, regulating body temperature, and homeostatic maintenance. Skin injuries can damage this important barrier and its functions so research focuses on approaches to accelerate wound healing and treat inflammatory skin diseases. Due to their regenerative and immunomodulatory properties, mesenchymal stromal cells (MSCs) have been reported to play a significant role in skin repair and regeneration. However, it seems that the secretome of these cells and exosomes in particular may be responsible for their functions in skin regeneration and the immunomodulation field. The present review aims to gather the available information about the role of MSC-derived exosomes for both in vitro and in vivo models of different skin conditions and to highlight the need for further research in order to overcome any limitations for clinical translation.es_ES
dc.description.sponsorshipCarlos III Health Institute of Spain [European Regional Development Fund "A way to make Europe"] PI13/02576 PI17/02083es_ES
dc.description.sponsorshipCarlos III Health Institute of Spain [Andalusian Regional Government Finance] PI13/02576 PI17/02083 SAS PI-0458-2016es_ES
dc.description.sponsorshipSpanish Ministry of Science, Innovation and Universities BOE 22/10/2019es_ES
dc.publisherFrontiers Research Foundationes_ES
dc.rightsAtribución 3.0 España*
dc.subjectExosomes-based therapyes_ES
dc.subjectMesenchymal stem cell-derived exosomeses_ES
dc.subjectRegenerative medicinees_ES
dc.subjectSkin autoimmune diseaseses_ES
dc.subjectSkin wound healinges_ES
dc.titleThe Role of Exosomes Derived From Mesenchymal Stromal Cells in Dermatologyes_ES

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Atribución 3.0 España
Except where otherwise noted, this item's license is described as Atribución 3.0 España