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dc.contributor.authorStallings, Elena
dc.contributor.authorGarcía Martín, Miguel Ángel
dc.identifier.citationStallings, E.; Antequera, A.; López-Alcalde, J.; García-Martín, M.; Urrútia, G.; Zamora, J. Sex as a Prognostic Factor in Systematic Reviews: Challenges and Lessons Learned. J. Pers. Med. 2021, 11, 441. jpm11060441es_ES
dc.description.abstractSex is a common baseline factor collected in studies that has the potential to be a prognostic factor (PF) in several clinical areas. In recent years, research on sex as a PF has increased; however, this influx of new studies frequently shows conflicting results across the same treatment or disease state. Thus, systematic reviews (SRs) addressing sex as a PF may help us to better understand diseases and further personalize healthcare. We wrote this article to offer insights into the challenges we encountered when conducting SRs on sex as a PF and suggestions on how to overcome these obstacles, regardless of the clinical domain. When carrying out a PF SR with sex as the index factor, it is important to keep in mind the modifications that must be made in various SR stages, such as modifying the PF section of CHARMS-PF, adjusting certain sections of QUIPS and extracting data on the sex and gender terms used throughout the studies. In this paper, we provide an overview of the lessons learned from carrying out our reviews on sex as a PF in different disciplines and now call on researchers, funding agencies and journals to realize the importance of studying sex as a PF.es_ES
dc.description.sponsorshipInstituto de Salud Carlos III (Plan Estatal de I + D + i 2013–2016)es_ES
dc.description.sponsorshipEuropean Development Regional Fund. “A way to achieve Europe” (ERDF) grant number PIE16/00050es_ES
dc.rightsAtribución 3.0 España*
dc.subjectSex es_ES
dc.subjectPrognosis es_ES
dc.subjectprognostic factores_ES
dc.subjectSystematic reviewes_ES
dc.subjectMethods es_ES
dc.titleSex as a Prognostic Factor in Systematic Reviews: Challenges and Lessons Learnedes_ES

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Atribución 3.0 España
Except where otherwise noted, this item's license is described as Atribución 3.0 España