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dc.contributor.authorQuílez Del Moral, José Francisco 
dc.contributor.authorPérez Rodríguez, Álvaro Adrián 
dc.contributor.authorSegura Navarro, María José
dc.contributor.authorGalisteo Pretel, Alberto
dc.contributor.authorFernández Barrero, Alejandro
dc.identifier.citationQuílez del Moral, J.F.; Pérez, Á.; Navarro, M.J.S.; Galisteo, A.; Gonzalez-Coloma, A.; Andrés, M.F.; Barrero, A.F. Selective Extraction of Bioactive Phenylethanoids from Digitalis obscura. Plants 2021, 10, 959. https://
dc.description.abstractCardenolide-free extracts from Digitalis obscura showed significant antifeedant effects against the aphid Myzus persicae and this activity correlated with their phenylethanoid content. The content in phenylethanoids of Digitalis obscura has been studied. Maceration of the aerial parts of D. obscura was used for the selective extraction of the natural compound rengyolone (1) and the aglycone of cornoside (compound 3). Pure rengyolone (1) can be obtained from D. obscura in approximately 90% purity from fresh plant from the CHCl3 soluble fraction of the ethanolic extract (0.8% yield). The ethanol extraction of freshly collected D. obscura showed the presence of compound 3 as the only phenylethanoid. Compound 3 was proven to easily evolve to rengyolone. Due to this instability, and although its presence in plants has been previously reported, the spectroscopical data of 3 are reported herein for the first time. Selective mono-acetylation of compound of 3 led to the active natural compound hallerone (5). The aphid antifeedant (against Myzus persicae) and nematicidal (against root-knot nematode Meloidogyne javanica) activities of these compounds have been evaluated. Here we report for the first time on the aphid antifeedant effects of 1, 3, and 5. Additionally, the nematicidal activity of hallerone (5) is described here for the first time.es_ES
dc.description.sponsorshipPID2019-106222RB-C32/SRA (State Research Agency, 10.13039/501100011033)es_ES
dc.description.sponsorshipPID2019- 106222RB-C31/SRA (State Research Agency, 10.13039/501100011033)es_ES
dc.description.sponsorshipERASMUS + N◦2018-1-FR01- KA202-047892 Biocontrol E Training (BET)es_ES
dc.description.sponsorshipUnidad Asociada UGR-CSIC Bioplaguicidas: Biotecnología, síntesis y diversidad químicaes_ES
dc.rightsAtribución 3.0 España*
dc.subjectSelective extractiones_ES
dc.subjectNatural productses_ES
dc.subjectPesticides es_ES
dc.titleSelective Extraction of Bioactive Phenylethanoids from Digitalis obscuraes_ES

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Atribución 3.0 España
Except where otherwise noted, this item's license is described as Atribución 3.0 España