Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-Analysis
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AuthorToledano Osorio, Manuel; Toledano Pérez, Manuel; Manzano Moreno, Francisco Javier; Vallecillo, Cristina; Vallecillo Rivas, Marta; Rodríguez Archilla, Alberto; Osorio Ruiz, Raquel
Bone regenerationPolymeric membraneBone substitutesRidge augmentation
Toledano-Osorio, M.; Toledano, M.; Manzano-Moreno, F.J.; Vallecillo, C.; Vallecillo-Rivas, M.; Rodriguez-Archilla, A.; Osorio, R. Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-Analysis. Polymers 2021, 13, 1172. [https://doi.org/10.3390/polym13071172]
SponsorshipMinistry of Economy and Competitiveness MINECO/FEDER MAT2017-85999P; European Commission MINECO/FEDER MAT2017-85999P A-BIO-157-UGR-18/FEDER; University of Granada/Regional Government of Andalusia Research Fund from Spain
Alveolar bone ridge resorption occurred after natural teeth loss and it can restrict the possibility of dental implants placement. The use of bone regenerative procedures is frequently required. The existing evidence regarding the efficacy of horizontal bone ridge augmentation trough guided bone regeneration (GBR) using polymeric membranes was stated. A systematic review and meta-analysis were performed. Electronic and manual literature searches were conducted. Screening process was done using the National Library of Medicine (MEDLINE by PubMed), Embase, and the Cochrane Oral Health. Included articles were randomized controlled trials and observational studies. Weighted means were calculated. Heterogeneity was determined using Higgins (I2). If I2 > 50% a random-effects model was applied. It was found that the mean of horizontal bone gain was 3.95 mm, ranging from 3.19 to 4.70 mm (confidence interval 95%). Heterogeneity is I2 = 99% (confidence interval 95%) and significance of the random-effects model was p < 0.001. The complications rate was 8.4% and membrane exposure was the most frequent. Through this study, we were able to conclude that the existing scientific evidence suggests that GBR using polymeric membranes is a predictable technique for achieving horizontal bone augmentation, thus, permitting a proper further implant placement.