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From Green Technology to Functional Olive Oils: Assessing the Best Combination of Olive Tree-Related Extracts with Complementary Bioactivities
dc.contributor.author | Hernáez, Álvaro | |
dc.contributor.author | Espejo Calvo, Juan Antonio | |
dc.contributor.author | Carrasco Pancorbo, Alegría | |
dc.contributor.author | Mesa García, María Dolores | |
dc.date.accessioned | 2021-03-25T09:16:26Z | |
dc.date.available | 2021-03-25T09:16:26Z | |
dc.date.issued | 2021-02 | |
dc.identifier.citation | Hernáez, Á.; Jaramillo, S.; García-Borrego, A.; Espejo-Calvo, J.A.; Covas, M.-I.; Blanchart, G.; de la Torre, R.; Carrasco-Pancorbo, A.; Mesa, M.D.; Fernández-Prior, M.Á.; et al. From Green Technology to Functional Olive Oils: Assessing the Best Combination of Olive Tree-Related Extracts with Complementary Bioactivities. Antioxidants 2021, 10, 202. [https://doi.org/10.3390/antiox10020202] | es_ES |
dc.identifier.uri | http://hdl.handle.net/10481/67688 | |
dc.description.abstract | Our aim was to assess the combination of olive tree-related extracts with the most favorable profile of in vitro bioactive properties. We tested the antioxidant (increment of low-density lipoprotein resistance against oxidation), vasoactive (promotion of nitric oxide release and decrease of endothelin-1 production in human umbilical vein endothelial cells), anti-inflammatory (decrease of the endothelial production of vascular cell adhesion molecule-1), and antithrombotic (reduction of the endothelial release of plasminogen activator inhibitor-1) capacities of six phenolic extracts and three triterpenic acid solutions (Ps and Ts, respectively). We tested extracts alone and in combination, at nutritional (Ps: 0.05–0.5 mol/L; Ts: 0.001–0.1 mol/L) and nutraceutical doses (Ps: 1–10 mol/L; Ts: 0.25–10 mol/L). The combination of Ps rich in 3,4-dihydroxyphenylglycol (76%, P2), hydroxytyrosol (95%, P3), and oleuropein (70%, P4) (final nutritional concentration: 0.15 mol/L; final nutraceutical concentration: 3 mol/L) was the best in order to prepare functional products and nutraceuticals with cardioprotective properties, despite the fact that the isolated extract with the greatest in vitro properties was P5 (75% oleocanthal), suggesting a potential synergistic effect among different olive components. | es_ES |
dc.description.sponsorship | Spanish Ministry of Economy, Industry and Competitiveness, through the FEDER INNTERCONECTA Program of the Center for Industrial Technological Development (CDTI) | es_ES |
dc.description.sponsorship | Junta de Andalucía ITC-20151142 EXP 00083147 | es_ES |
dc.description.sponsorship | Instituto de Salud Carlos III European Commission CB06/03/0028 CD17/00122 CES12/025 JR17/00022 | es_ES |
dc.description.sponsorship | European Commission | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Mdpi | es_ES |
dc.rights | Atribución 3.0 España | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.subject | Olive tree | es_ES |
dc.subject | Phenolic compounds | es_ES |
dc.subject | Triterpenes | es_ES |
dc.subject | Bioactivity | es_ES |
dc.subject | Functional olive oil | es_ES |
dc.subject | 3,4-dihydroxyphenylglycol | es_ES |
dc.subject | Hydroxytyrosol | es_ES |
dc.subject | Oleuropein | es_ES |
dc.subject | Oleocanthal | es_ES |
dc.title | From Green Technology to Functional Olive Oils: Assessing the Best Combination of Olive Tree-Related Extracts with Complementary Bioactivities | es_ES |
dc.type | journal article | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.identifier.doi | 10.3390/antiox10020202 | |
dc.type.hasVersion | VoR | es_ES |