Show simple item record

dc.contributor.authorBernal Benítez, Antonio 
dc.contributor.authorMateo-Martínez, Raquel
dc.contributor.authorPaolieri, Daniela
dc.date.accessioned2021-03-18T09:18:19Z
dc.date.available2021-03-18T09:18:19Z
dc.date.issued2020
dc.identifier.urihttp://hdl.handle.net/10481/67305
dc.description.abstractThis study examines the influence of sex, menstrual cycle, hormonal contraceptives (HC) and sex hormone levels in following egocentric navigation instructions with or without landmarks. Estradiol seem to bias the reference frame for navigation during estrous cycle of female rats. However, previous studies in humans found no differences in overall navigation between women in their early follicular and mid-luteal menstrual cycle phases, whose performance was worse than that of men. Our study hypothesis was that the performance of women would be improved during the peri-ovulatory phase and would remain the same during placebo and active phases of HC users. The study included 21 men, 62 women with natural menstrual cycle (21 during early follicular phase, 20 during periovulatory phase, and 21 during mid-luteal phase), and 38 women that were receiving HC (13 during placebo phase and 25 during active phase). The men outperformed the women with a natural menstrual cycle when following egocentric instructions without landmarks. However, the women’s performance varied according to the phase of their menstrual cycle, differing from men during early follicular and mid-luteal phases but not during the peri-ovulatory phase. The use of HC also improved the performance of women to the extent that the difference with men disappeared. No differences were observed between HC-placebo and HC-active user groups during egocentric navigation without landmarks and among all groups during egocentric navigation with landmarks. Analysis of salivary hormones showed that testosterone levels were higher in men and that estradiol levels in women were higher during peri-ovulatory and mid-luteal phases and also in HC users. Progesterone levels were higher in women during the mid-luteal phase. These results appear compatible with beneficial effect of testosterone and estradiol on egocentric navigation without landmarks and with a block of this effect produced by progesterone.es_ES
dc.language.isoenges_ES
dc.subjectEgocentric navigationes_ES
dc.subjectLandmarkses_ES
dc.subjectSex differences es_ES
dc.subjectMenstrual cycle phasees_ES
dc.subjectHormonal contraceptiveses_ES
dc.subjectSex hormoneses_ES
dc.titleInfluence of sex, menstrual cycle, and hormonal contraceptives on egocentric navigation with or without landmarkses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doihttps://doi.org/10.1016/j.psyneuen.2020.104768


Files in this item

[PDF]

This item appears in the following Collection(s)

Show simple item record