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dc.contributor.authorToledano Pérez, Manuel 
dc.contributor.authorOsorio Ruiz, Raquel 
dc.contributor.authorVallecillo-Rivas, Marta
dc.contributor.authorOsorio Ruiz, María Estrella 
dc.contributor.authorLynch, Christopher D.
dc.contributor.authorAguilera, Fátima S.
dc.contributor.authorToledano, Raquel
dc.contributor.authorSauro, Salvatore
dc.identifier.citationPublisher version: Toledano M, Osorio R, Vallecillo-Rivas M, Osorio E, Lynch CD, Aguilera FS, Toledano R, Sauro S. Zn-doping of silicate and hydroxyapatite-based cements: Dentin mechanobiology and bioactivity. Journal of the Mechanical Behavior of Biomedical Materials. 2021;114:104232.es_ES
dc.descriptionThis work was supported by the Ministry of Economy and Competitiveness and European Regional Development Fund [MAT2017-85999PMINECO/AEI/FEDER/UE]. The authors affirm that no actual or potential conflict of interest including any financial, personal or other relationships with other people or organizations within three years of beginning the submitted work that could inappropriately influence, or be perceived to influence, their work. Any other potential conflict of interest is disclosed.es_ES
dc.description.abstractThe objective was to state zinc contribution in the effectiveness of novel zinc-doped dentin cements to achieve dentin remineralization, throughout a literature or narrative exploratory review. Literature search was conducted using electronic databases, such as PubMed, MEDLINE, DIMDI, Embase, Scopus and Web of Science. Both zinc-doping silicate and hydroxyapatite-based cements provoked an increase of both bioactivity and intrafibrillar mineralization of dentin. Zinc-doped hydroxyapatite-based cements (oxipatite) also induced an increase in values of dentin nano-hardness, Young’s modulus and dentin resistance to deformation. From Raman analyses, it was stated higher intensity of phosphate peaks and crystallinity as markers of dentin calcification, in the presence of zinc. Zinc-based salt formations produced low microleakage and permeability values with hermetically sealed tubules at radicular dentin. Dentin treated with oxipatite attained preferred crystal grain orientation with polycrystalline lattices. Thereby, oxipatite mechanically reinforced dentin structure, by remineralization. Dentin treated with oxipatite produced immature crystallites formations, accounting for high hydroxyapatite solubility, instability and enhanced remineralizing activity.es_ES
dc.description.sponsorshipThis work was supported by the Ministry of Economy and Competitiveness and European Regional Development Fund [MAT2017-85999PMINECO/AEI/FEDER/UE].es_ES
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.subjectZinc es_ES
dc.subjectCement es_ES
dc.title[EMBARGADO HASTA FEB 2023]Zn-doping of silicate and hydroxyapatite-based cements: dentin mechanobiology and bioactivityes_ES

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Atribución-NoComercial-SinDerivadas 3.0 España
Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 3.0 España