Growth Factors in Oral Tissue Engineering: New Perspectives and Current Therapeutic Options
Metadatos
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HINDAWI LTD
Fecha
2021Referencia bibliográfica
Luca Fiorillo, Gabriele Cervino, Pablo Galindo-Moreno, Alan Scott Herford, Gianrico Spagnuolo, Marco Cicciù, "Growth Factors in Oral Tissue Engineering: New Perspectives and Current Therapeutic Options", BioMed Research International, vol. 2021, Article ID 8840598, 11 pages, 2021. https://doi.org/10.1155/2021/8840598
Resumen
The present investigation is aimed at systematically analyzing the recent literature about the innovative scaffold involved in the
reconstructive surgeries by applying growth factors and tissue engineering. An extensive review of the contemporary literature
was conducted according to the PRISMA guidelines by accessing the PubMed, Embase, and Scopus Elsevier databases. Authors
performed the English language manuscript research published from 2003 to 2020. A total of 13 relevant studies were included
in the present review. The present systematic review included only papers with significant results about correlation between
scaffold, molecular features of growth factor, and reconstructive surgeries in oral maxillofacial district. The initial research with
filters recorded about 1023 published papers. Beyond reading and considering of suitability, only 42 and then 36 full-text papers
were recorded for the revision. All the researches recorded the possibility of using growth factors on rebuilding atrophic jaws.
Different growth factors like morphogenetic factors, cytokines, and inflammatory ones and their application over different
scaffold materials were recorded. Further investigations should be required in order to state scientific evidence about a clear
advantage of applying tissue engineering for therapeutic purpose.