Mostrar el registro sencillo del ítem

dc.contributor.authorCasuso Pérez, Rafael Antonio
dc.contributor.authorRodríguez Huertas, Jesús Francisco 
dc.date.accessioned2021-02-25T10:25:29Z
dc.date.available2021-02-25T10:25:29Z
dc.date.issued2021-01-15
dc.identifier.citationCasuso, R.A.; Huertas, J.R. Mitochondrial Functionality in Inflammatory Pathology-Modulatory Role of Physical Activity. Life 2021, 11, 61. [https://doi.org/10.3390/ life11010061]es_ES
dc.identifier.urihttp://hdl.handle.net/10481/66720
dc.description.abstractThe incidence and severity of metabolic diseases can be reduced by introducing healthy lifestyle habits including moderate exercise. A common observation in age-related metabolic diseases is an increment in systemic inflammation (the so-called inflammaging) where mitochondrial reactive oxygen species (ROS) production may have a key role. Exercise prevents these metabolic pathologies, at least in part, due to its ability to alter immunometabolism, e.g., reducing systemic inflammation and by improving immune cell metabolism. Here, we review how exercise regulates immunometabolism within contracting muscles. In fact, we discuss how circulating and resident macrophages alter their function due to mitochondrial signaling, and we propose how these effects can be triggered within skeletal muscle in response to exercise. Finally, we also describe how exercise-induced mitochondrial adaptations can help to fight against virus infection. Moreover, the fact that moderate exercise increases circulating immune cells must be taken into account by public health agencies, as it may help prevent virus spread. This is of interest in order to face not only acute respiratory-related coronavirus (SARS-CoV) responsible for the COVID-19 pandemic but also for future virus infection challenges.es_ES
dc.language.isoenges_ES
dc.publisherMdpies_ES
dc.rightsAtribución 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectExercise es_ES
dc.subjectMitochondriaes_ES
dc.subjectImmune systemes_ES
dc.subjectMetabolic diseasees_ES
dc.subjectCOVID-19es_ES
dc.titleMitochondrial Functionality in Inflammatory Pathology-Modulatory Role of Physical Activityes_ES
dc.typejournal articlees_ES
dc.rights.accessRightsopen accesses_ES
dc.identifier.doi10.3390/ life11010061
dc.type.hasVersionVoRes_ES


Ficheros en el ítem

[PDF]

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

Atribución 3.0 España
Excepto si se señala otra cosa, la licencia del ítem se describe como Atribución 3.0 España