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dc.contributor.authorGarcía Torrecillas, Juan Manuel
dc.contributor.authorSánchez, María José
dc.identifier.citationGarcía-Torrecillas, J.M.; Olvera-Porcel, M.C.; Ferrer-Márquez, M.; Rosa-Garrido, C.; Rodríguez-Barranco, M.; Lea-Pereira, M.C.; Rubio-Gil, F.; Sánchez, M.-J. Predictive Model of the Risk of In-Hospital Mortality in Colorectal Cancer Surgery, Based on the Minimum Basic Data Set. Int. J. Environ. Res. Public Health 2020, 17, 4216.
dc.description.abstractBackground: Various models have been proposed to predict mortality rates for hospital patients undergoing colorectal cancer surgery. However, none have been developed in Spain using clinical administrative databases and none are based exclusively on the variables available upon admission. Our study aim is to detect factors associated with in-hospital mortality in patients undergoing surgery for colorectal cancer and, on this basis, to generate a predictive mortality score. Methods: A population cohort for analysis was obtained as all hospital admissions for colorectal cancer during the period 2008–2014, according to the Spanish Minimum Basic Data Set. The main measure was actual and expected mortality after the application of the considered mathematical model. A logistic regression model and a mortality score were created, and internal validation was performed. Results: 115,841 hospitalization episodes were studied. Of these, 80% were included in the training set. The variables associated with in-hospital mortality were age (OR: 1.06, 95%CI: 1.05–1.06), urgent admission (OR: 4.68, 95% CI: 4.36–5.02), pulmonary disease (OR: 1.43, 95%CI: 1.28–1.60), stroke (OR: 1.87, 95%CI: 1.53–2.29) and renal insufficiency (OR: 7.26, 95%CI: 6.65–7.94). The level of discrimination (area under the curve) was 0.83. Conclusions: This mortality model is the first to be based on administrative clinical databases and hospitalization episodes. The model achieves a moderate–high level of discrimination.es_ES
dc.description.sponsorshipCarlos III Institute of Health, Madrid (Spain) under the 2013-2016 National Plan for RDI PI16/01931es_ES
dc.description.sponsorshipISCIII-General Subdirectorate for Evaluation and Promotion of Research, within the European Regional Development Fund (FEDER)es_ES
dc.rightsAtribución 3.0 España*
dc.subjectPredictive modelses_ES
dc.subjectColorectal canceres_ES
dc.subjectEpidemiology es_ES
dc.subjectPublic health es_ES
dc.subjectMortality es_ES
dc.titlePredictive Model of the Risk of In-Hospital Mortality in Colorectal Cancer Surgery, Based on the Minimum Basic Data Setes_ES

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Atribución 3.0 España
Except where otherwise noted, this item's license is described as Atribución 3.0 España