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The antibiotic crisis: How bacterial predators can help
dc.contributor.author | Pérez Torres, Juana | |
dc.contributor.author | Contreras Moreno, Francisco Javier | |
dc.contributor.author | Marcos Torres, Francisco Javier | |
dc.contributor.author | Moraleda Muñoz, Aurelio | |
dc.contributor.author | Muñoz Dorado, José | |
dc.date.accessioned | 2021-02-15T09:27:48Z | |
dc.date.available | 2021-02-15T09:27:48Z | |
dc.date.issued | 2020-09-15 | |
dc.identifier.citation | J. Pérez et al. The antibiotic crisis: How bacterial predators can help. Computational and Structural Biotechnology Journal 18 (2020) 2547–2555 [https://doi.org/10.1016/j.csbj.2020.09.010] | es_ES |
dc.identifier.uri | http://hdl.handle.net/10481/66546 | |
dc.description | This work has been supported by the Spanish Government, grant BFU2016-75425-P to Aurelio Moraleda-Munoz (70% funded by FEDER). Funder has no involvement in study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the article for publication. We thank Lola Contreras-Moreno for technical assistance with Fig. 1. | es_ES |
dc.description.abstract | Discovery of antimicrobials in the past century represented one of the most important advances in public health. Unfortunately, the massive use of these compounds in medicine and other human activities has promoted the selection of pathogens that are resistant to one or several antibiotics. The current antibiotic crisis is creating an urgent need for research into new biological weapons with the ability to kill these superbugs. Although a proper solution requires this problem to be addressed in a variety of ways, the use of bacterial predators is emerging as an excellent strategy, especially when used as whole cell therapeutic agents, as a source of new antimicrobial agents by awakening silent metabolic pathways in axenic cultures, or as biocontrol agents. Moreover, studies on their prey are uncovering mechanisms of resistance that can be shared by pathogens, representing new targets for novel antimicrobial agents. In this review we discuss potential of the studies on predator-prey interaction to provide alternative solutions to the problem of antibiotic resistance. | es_ES |
dc.description.sponsorship | Spanish Government BFU2016-75425-P | es_ES |
dc.description.sponsorship | European Union (EU) | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.rights | Atribución-NoComercial-SinDerivadas 3.0 España | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject | Antibiotic crisis | es_ES |
dc.subject | Bacterial predators | es_ES |
dc.subject | BALOs | es_ES |
dc.subject | Myxobacteria | es_ES |
dc.title | The antibiotic crisis: How bacterial predators can help | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.identifier.doi | 10.1016/j.csbj.2020.09.010 | |
dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | es_ES |