Data supporting the physico-chemical characterization, cellular uptake and cytotoxicity of lipid nanocapsules
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AuthorSánchez Moreno, Paola; Ortega Vinuesa, Juan Luis; Boulaiz Tassi, Houria; Marchal Corrales, Juan Antonio; Peula-García, José Manuel
P. Sánchez-Moreno et al. Data supporting the physico-chemical characterization, cellular uptake and cytotoxicity of lipid nanocapsules. Data in Brief 4 (2015) 279–284 [http://dx.doi.org/10.1016/j.dib.2015.06.002]
SponsorshipEuropean Union (EU) MAT2010-20370 MAT2013-43922-R; Instituto de Salud Carlos III, Fondo de Investigacion Sanitaria, FEDER funds PI10/02295; Junta de Andalucia P07-FQM2496 P10-CTS-6270 P07-FQM3099; Spanish Government
The aim of this data article is to provide data for a basic knowledge of the properties of lipid nanocapsules, a new colloidal system with very promising applications in drug delivery. Firstly, we pay attention on how it is possible to determine their surface composition by means of electrokinetics measurements. On the other hand, we provide experimental evidences for a better understanding of the factors that determine the interactions of these nanoparticles with cells as a necessary step to guide the design of the most effective formulations. Additionally, we supply information about encapsulation efficiency of docetaxel, a potent chemotherapy drug, inside nanocapsules supporting the experimental cytotoxicity results of these nanosystems.