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dc.contributor.authorAltmae, Signe 
dc.contributor.authorMolina Morales, Nerea 
dc.date.accessioned2021-01-20T13:00:42Z
dc.date.available2021-01-20T13:00:42Z
dc.date.issued2020-12-25
dc.identifier.citationAltmäe, S., Molina, N. M., & Sola-Leyva, A. (2020). Omission of non-poly (A) viral transcripts from the tissue level atlas of the healthy human virome. BMC biology, 18(1), 1-3. [doi:10.1186/s12915-020-00907-z]
dc.identifier.urihttp://hdl.handle.net/10481/65853
dc.description.abstractA recent paper in BMC Biology entitled “A tissue level atlas of the healthy human virome” by Kumata et al. describes a meta-transcriptomic analysis of RNA-sequencing datasets from the Genotype-Tissue Expression (GTEx) Project. Using a workflow that maps the GTEx sequences to the human genome, then screens unmapped sequences to detect viral transcripts, the authors present a quantitative analysis of the presence of different viruses in the nondiseased tissues of over 500 individuals and assess the impact of these viruses on host gene expression. Here we draw attention to an issue not acknowledged in this study. Namely, by relying solely on GTEx datasets, which are enriched for transcripts with poly(A) tails, the analysis will have missed non-poly(A) viral transcripts, rendering this tissue level atlas of the virome incompletees_ES
dc.description.sponsorshipSpanish Ministry of Economy, Industry and Competitiveness (MINECO)es_ES
dc.description.sponsorshipEuropean Union (EU) RYC-2016-21199 ENDORE SAF2017-87526-Res_ES
dc.description.sponsorshipFEDER/Junta de Andalucía -Consejería de Economía y Conocimiento: MENDO B-CTS-500-UGR18es_ES
dc.description.sponsorshipUniversity of Granada Plan Propio de Investigacion 2016 -Excellence actions: Unit of Excellence on Exercise and Health (UCEES) SOMM17/6107/UGRes_ES
dc.description.sponsorshipSpanish Ministry of Science, Innovation and Universities PRE2018-0854409 FPU19/01638es_ES
dc.language.isoenges_ES
dc.publisherSpringer Naturees_ES
dc.rightsAtribución 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectGTExes_ES
dc.subjectPoly(A) tailes_ES
dc.subjectRNA-Seqes_ES
dc.subjectVirus es_ES
dc.subjectViromees_ES
dc.titleOmission of non-poly(A) viral transcripts from the tissue level atlas of the healthy human viromees_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.1186/s12915-020-00907-z
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones_ES


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