Inter‑ and intra‑researcher reproducibility of heart rate variability parameters in three human cohorts
Metadatos
Mostrar el registro completo del ítemEditorial
Nature Research
Fecha
2020-07-09Referencia bibliográfica
Plaza-Florido, A., Alcantara, J. M. A., Migueles, J. H., Amaro-Gahete, F. J., Acosta, F. M., Mora-Gonzalez, J., ... & Ortega, F. B. (2020). Inter-and intra-researcher reproducibility of heart rate variability parameters in three human cohorts. Scientific reports, 10(1), 1-11. [https://doi.org/10.1038/s41598-020-68197-7]
Patrocinador
Spanish Ministry of Economy and Competitiveness DEP2013-47540 DEP2016-79512-R PTA 12264-I; Spanish Ministry of Education, Culture and Sport FPU 16/02760 FPU15/02645 FPU15/04059 FPU14/06837 FPU14/04172; Unit of Excellence on Exercise and Health (UCEES); EXERNET Research Network on Exercise and Health in Special Populations DEP2005-00046/ACTI; Unit of Excellence in Sport and Health (UCEES) - University of Granada; Junta de Andalucía; European Union (EU) SOMM17/6107/UGRResumen
Heart rate variability (HRV) is a valid and non-invasive indicator of cardiac autonomic nervous system
functioning. Short-term HRV recordings (e.g., 10 min long) produce data that usually is manually
processed. Researcher subjective decision-making on data processing could produce inter- or intraresearcher
differences whose magnitude has not been previously quantified in three independent
human cohorts. This study examines the inter- and intra-researcher reproducibility of HRV parameters
(i.e., the influence of R–R interval selection by different researchers and by the same researcher in
different moments on the quantification of HRV parameters, respectively) derived from short-term
recordings in a cohort of children with overweight/obesity, young adults and middle-age adults.
Participants were recruited from 3 different studies: 107 children (10.03 ± 1.13 years, 58% male), 132
young adults (22.22 ± 2.20 years, 33% males) and 73 middle-aged adults (53.62 ± 5.18 years, 48%
males). HRV was measured using a Polar RS800CX heart rate monitor. The intraclass correlation
coefficient (ICC) ranged from 0.703 to 0.989 and from 0.950 to 0.998 for inter-and intra-researcher
reproducibility, respectively. Limits of agreement for HRV parameters were higher for the interresearcher
processing compared with the intra-researcher processing. On average, the intraresearcher
differences were 31%, 62%, and 80% smaller than the inter-researchers differences based
on Coefficient of Variation in children, young and middle-aged adults, respectively. Our study provides
the quantification of the inter-researcher and intra-researcher differences in three independent
human cohorts, which could elicit some clinical relevant differences for HRV parameters. Based on our
findings, we recommend the HRV data signal processing to be performed always by the same trained
researcher and we postulate a development of algorithms for an automatic ECG selection.