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      Financiación
      J.D.T. was supported by a Ph.D. studentship from TheCunningham Trust. J.W.D. was supported by an NHSResearch Scotland (NRS) Career Research Fellowship throughNHS Lothian and acknowledges the contribution of the BritishHeart Foundation Centre of Research Excellence Award (RE/08/001). This research was partially supported by the Ministryof Economy and Competitiveness, Spain (BIO2016-80519-R)and Health Insitute Carlos III (ISCIII) (Projects oftechnological development in health - ref DTS18/00121). [1]
      This research was supported by funding from the Spanish Ministry of Economy and Competitiveness (BIO2016-80519, PID2019.110987RB.I00); the Health Institute Carlos III (DTS18/00121); the Andalusian Regional Government-FEDER (PT18-TP-4160, B-FQM-475-UGR18, A-FQM-760-UGR20); the Department of Defense (W81XWH-12-1-0591); NCI (1R01CA234553, R21CA231280); the 2019 Cancer Innovation Award, supported by the Stanford Cancer Institute, an NCI-designated Comprehensive Cancer Center; BRCA Foundation and the V Foundation for Cancer Research; a gift from the Gray Foundation; the Department of Urology at Stanford University; NHLBI (P01HL10879709); NIAID (U19AI057229); and a PICI Bedside to Bench grant. R.M.S.-M., J.J.D.-M., M.V.C.-C., and J.A.L.-R. are members of the network NANOCARE (RED2018-102469-T) funded by the Spanish State Research Agency. W.J.F. thanks the BRCA Foundation and the V Foundation for Cancer Research, a gift from the Gray Foundation and the Department of Urology at Stanford University. A.D.-G. thanks the Spanish Ministry of Education for PhD funding (scholarship FPU14/02181), the University of Granada for postdoctoral research contract, and the Fundación Alfonso Martín Escudero for his postdoctoral fellowship. J.A.L.-R. thanks the Fundación Benéfica Anticancer San Francisco Javier y Santa Candida for PhD funding. M.V.C.-C. thanks the Andalusian Regional Government for her postdoctoral fellowship (POSTDOC_21_00118). The authors thank the technical support from the Cytometry unit of GENYO. The graphical abstract and Figures 5a and 6a have been created with BioRender.com. [1]
      This research was supported by the Regional Government, Spain(BIO-1778) and the Ministry of Economy and Competitiveness, Spain(BIO2016-80519-R – FJLD is supported by Torres Quevedo fellowship,SpainPTQ-16-08597).ADGandARRaresupportedbySpanishMinistryof Education, Spain (PhD scholarships FPU14/02181 and FPU15/06418, respectively). AMR thanks DestiNA Genomics, Spain and theUniversity of Granada, Spain for a PhD scholarship (P26 KnowledgeTransferProgramme)DMPacknowledgestheUniversityofGranadaforhis predoctoral research contract. SD's work was supported by in-tramural funding from the University of Trento, Italy. DestiNA's staffand SD thank the miRNADisEASY Consortium (EU, European UnionH2020-MSCA-RISE 2015 (Grant no. 690866)). We would also like tothank all the healthy volunteers who participated in this study. [1]
      This research was supported by the Spanish Ministry of Economy and Competitiveness (grant number BIO2016-80519). The authors are members of the NANOCARE network (RED2018-102469-T) funded by the STATE INVESTIGATION AGENCY. ARR thanks the Spanish Ministry of Education for PhD funding (scholarship FPU15/06418). FJ Lopez Delgado thanks the Spanish Ministry of Economy and Competitiveness for the Torres Quevedo fellowship (PTQ-16- 08597). These studies were approved and supported by DestiNA Genomics Ltd. Schemes in Figs. 1 and 4–6 have been partially created using BioRender.com. [1]
      This research was supported by the Spanish Ministry of Economy and Competitiveness (grant number BIO2016-80519-R, PID2019.110987RB.I00); the Andalusian Regional Government-FEDER (PT18-TP-4160, B-FQM-475-UGR18, A-FQM-760-UGR20); the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie actions (MSCA-RISE-101007934). The authors are members of the NANOCARE network (RED2018-102469-T) funded by the State Investigation Agency. ARR thanks the Spanish Ministry of Education for PhD funding (scholarship FPU15/06418) and the University of Granada for postdoctoral research. FJ López-Delgado thanks the Spanish Ministry of Economy and Competitiveness for the Torres Quevedo fellowship (PTQ-16-08597). These studies were approved and supported by DESTINA Genomics Ltd. Schemes in Graphical abstract and Fig. 1 have been partially created using BioRender.com. We thank Raquel Marrero-Díaz for her valuable support in the microscopy analyses. [1]
      This research work has received funding from Junta de Andalucía, Consejería de Economía e Innovación (project number 2012- BIO1778), the Spanish Ministerio de Economía y Competitividad (Grants CTQ2012-34778, BIO2016-80519-R, FPI Grant BES-2013- 063020). This research was partially supported by the 7th European Community Framework Program (FP7-PEOPLE-2012-CIG-Project Number 322276). The authors thank DestiNA Genomica S.L. for assistance during the process of isolation of the genomic DNA, PCR amplification and dynamic chemistry reaction. We also thank Carlos Rodrigues-Poveda for technical advice and Mr. Hugh Ilyine for proof-reading. [1]