Clinical Factors, Preventive Behaviours and Temporal Outcomes Associated with COVID-19 Infection in Health Professionals at a Spanish Hospital
Metadatos
Mostrar el registro completo del ítemAutor
Rivera Izquierdo, Mario; Valero Ubierna, María del Carmen; Martínez Diz, Silvia; Fernández García, Miguel Ángel; Martín Romero, Divina Tatiana; Maldonado Rodríguez, Francisco; Sánchez Pérez, María Rosa; Martín de los Reyes, Luis Miguel; Martínez Ruiz, Virginia Ana; Lardelli Claret, Pablo; Jiménez Mejías, EladioEditorial
MDPI
Materia
Follow-up Healthcare Professionals COVID-19 SARS-CoV-2 PCR Negativization
Fecha
2020-06-16Referencia bibliográfica
Rivera-Izquierdo, M., Valero-Ubierna, M. D. C., Martínez-Diz, S., Fernández-García, M. Á., Martín-Romero, D. T., Maldonado-Rodríguez, F., ... & Jiménez-Mejías, E. (2020). Clinical Factors, Preventive Behaviours and Temporal Outcomes Associated with COVID-19 Infection in Health Professionals at a Spanish Hospital. International journal of environmental research and public health, 17(12), 4305. [doi: 10.3390/ijerph17124305]
Patrocinador
Chair of Teaching and Research in Family Medicine SEMERGEN-UGR. University of GranadaResumen
The novel coronavirus disease (COVID-19) outbreak has quickly spread around the world,
with Spain being one of the most severely affected countries. Healthcare professionals are an important
risk group given their exposure. The aims of this study were to determine the prevalence of symptoms,
main concerns as patients, preventive behaviours of healthcare professionals, and the different
temporal outcomes associated with the negativization of PCR results. A total of 238 professionals
were analysed and follow-up was conducted from 11 March to 21 April 2020 through clinical
records, in-depth surveys, and telephone interviews. Symptoms, concerns, and preventive measures
were documented, and temporal outcomes (start and end of symptoms, first positive PCR, and
negativization of PCR) were analysed through survival analyses. A high prevalence of gastrointestinal
symptoms (especially in women and older professionals), fever, cough, and fatigue were reported.
The main concern was contagion in the work and home environment. Professionals (especially men)
reported low use of face masks before the pandemic. Our analysis indicates that the median times for
the negativization of PCR testing to confirm the resolution of infection is 15 days after the end of
symptoms, or 25 days after the first positive PCR test. Our results suggest that these times are longer
for women and for professionals aged ≥55 years, therefore follow-up strategies should be optimized
in light of both variables. This is the first study we are aware of to report factors associated with
the time to negativization of PCR results. We present the first rigorous estimates of time outcomes
and hope that these data can be valuable to continue feeding the prediction models that are currently
being developed. Similar studies are required to corroborate our results.