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dc.contributor.authorMut Salud, Nuria
dc.contributor.authorÁlvarez-Aránega, Pablo
dc.contributor.authorGarrido Jiménez, José Manuel 
dc.contributor.authorCarrasco, Esther
dc.contributor.authorAránega Jiménez, Antonia 
dc.contributor.authorRodríguez Serrano, Fernando 
dc.date.accessioned2020-07-24T11:16:23Z
dc.date.available2020-07-24T11:16:23Z
dc.date.issued2015-11-22
dc.identifier.citationMut-Salud, N., Álvarez, P. J., Garrido, J. M., Carrasco, E., Aránega, A., & Rodríguez-Serrano, F. (2016). Antioxidant intake and antitumor therapy: toward nutritional recommendations for optimal results. Oxidative medicine and cellular longevity, 2016. [https://doi.org/10.1155/2016/6719534]es_ES
dc.identifier.urihttp://hdl.handle.net/10481/63126
dc.descriptionThis study was supported by the Regional Government of Andalusia (Project P11-CTS-7651 and assistance to the CTS-107 group).es_ES
dc.description.abstractThe role of the induction of oxidative stress as the mechanism of action of many antitumor drugs is acquiring an increasing interest. In such cases, the antitumor therapy success may be conditioned by the antioxidants present in our own body, which can be synthesized de novo (endogenous) or incorporated through the diet and nutritional supplements (exogenous). In this paper, we have reviewed different aspects of antioxidants, including their classification, natural sources, importance in diet, consumption of nutritional supplements, and the impact of antioxidants on health. Moreover, we have focused especially on the study of the interaction between antioxidants and antitumor therapy, considering both radiotherapy and chemotherapy. In this regard, we found that the convenience of administration of antioxidants during cancer treatment still remains a very controversial issue. In general terms, antioxidants could promote or suppress the effectiveness of antitumor treatment and even protect healthy tissues against damage induced by oxidative stress. The effects may depend on many factors discussed in the paper. These factors should be taken into consideration in order to achieve precise nutritional recommendations for patients. The evidence at the moment suggests that the supplementation or restriction of exogenous antioxidants during cancer treatment, as appropriate, could contribute to improving its efficiency.es_ES
dc.description.sponsorshipJunta de Andalucia P11-CTS-7651es_ES
dc.language.isoenges_ES
dc.publisherHindawies_ES
dc.rightsAtribución 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.titleAntioxidant Intake and Antitumor Therapy: Toward Nutritional Recommendations for Optimal Resultses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.1155/2016/6719534
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones_ES


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