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dc.contributor.authorCaparrós González, Rafael Arcángel 
dc.contributor.authorRomero González, Borja
dc.contributor.authorPeralta Ramírez, María Isabel 
dc.contributor.authorGonzález Pérez, Raquel 
dc.contributor.authorGarcía Velasco, Juan Antonio
dc.date.accessioned2020-06-12T12:49:02Z
dc.date.available2020-06-12T12:49:02Z
dc.date.issued2020-04
dc.identifier.citationC Santa-Cruz, D., Caparros-Gonzalez, R. A., Romero-Gonzalez, B., Peralta-Ramirez, M. I., Gonzalez-Perez, R., & García-Velasco, J. A. (2020). Hair Cortisol Concentrations as a Biomarker to Predict a Clinical Pregnancy Outcome after an IVF Cycle: A Pilot Feasibility Study. International Journal of Environmental Research and Public Health, 17(9), 3020. [doi:10.3390/ijerph17093020]es_ES
dc.identifier.urihttp://hdl.handle.net/10481/62457
dc.descriptionWe would also like to thank our research nurses M.M. and Y.G. for their support during follow-up.es_ES
dc.description.abstractOur objective was to examine the feasibility of hair cortisol concentrations (HCC) as a biomarker to predict clinical pregnancy outcomes and investigate its potential associations with perceived anxiety, resilience, and depressive symptoms. A total of 43 participants were assessed using HCC, the state trait anxiety inventory (STAI), resilience scale (RS), and the depression subscale of the symptom checklist 90-R (SCL-90-R). Participants were approached at their second consultation with the reproductive endocrinologist (T1), before scheduling their IVF cycle, and then 12 weeks after (T2), at their post-transfer visit with the study coordinators, before the human chorionic gonadotropin (HCG) pregnancy test. The logistic regression model revealed that HCC at T2 predicted 46% of a positive pregnancy test [R2 = 0.46, (ß = 0.11, p < 0.05)]. Pregnant women had higher levels of resilience at T2 (M = 149.29; SD = 17.56) when compared with non-pregnant women at T2 (M = 119.96; SD = 21.71). Significant differences were found between both groups in depression at T2 (t = 3.13, p = 0.01) and resilience at T2 (t = −4.89, p = 0.01). HCC might be a promising biomarker to calculate the probability of pregnancy in women using assisted reproductive technologies (ART).es_ES
dc.description.sponsorshipThis study is part of a doctoral thesis, with funds for an I+D project from IVI Foundation/IVI-RMA Innovation, reference number 1405-MAD-027-DS.es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsAtribución 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectInfertility es_ES
dc.subjectPregnancy es_ES
dc.subjectCortisoles_ES
dc.subjectStress es_ES
dc.titleHair Cortisol Concentrations as a Biomarker to Predict a Clinical Pregnancy Outcome after an IVF Cycle: A Pilot Feasibility Studyes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doidoi:10.3390/ijerph17093020


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