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COVID-19: A Recommendation to Examine the Effect of Mouthrinses with β-Cyclodextrin Combined with Citrox in Preventing Infection and Progression
dc.contributor.author | Llodra Calvo, Juan Carlos | |
dc.contributor.author | Carrouel, Florence | |
dc.date.accessioned | 2020-06-05T11:39:04Z | |
dc.date.available | 2020-06-05T11:39:04Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Carrouel, F., Conte, M. P., Fisher, J., Gonçalves, L. S., Dussart, C., Llodra, J. C., & Bourgeois, D. (2020). COVID-19: A Recommendation to Examine the Effect of Mouthrinses with β-Cyclodextrin Combined with Citrox in Preventing Infection and Progression. [doi:10.3390/jcm9041126] | es_ES |
dc.identifier.uri | http://hdl.handle.net/10481/62378 | |
dc.description.abstract | Considered to be a major portal of entry for infectious agents, the oral cavity is directly associated with the evolutionary process of SARS-CoV-2 in its inhalation of ambient particles in the air and in expectorations. Some new generations of mouth rinses currently on the market have ingredients that could contribute to lower the SARS-CoV-2 viral load, and thus facilitate the fight against oral transmission. If chlorhexidine, a usual component of mouth rinse, is not efficient to kill SARS-CoV-2, the use of a mouth rinses and/or with local nasal applications that contain β-cyclodextrins combined with flavonoids agents, such as Citrox, could provide valuable adjunctive treatment to reduce the viral load of saliva and nasopharyngeal microbiota, including potential SARS-CoV-2 carriage. We urge national agencies and authorities to start clinical trials to evaluate the preventive effects of βCD-Citrox therapeutic oral biofilm rinses in reducing the viral load of the infection and possibly disease progression. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | Atribución 3.0 España | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.subject | COVID-19 | es_ES |
dc.subject | 2019-nCoV | es_ES |
dc.subject | SARS-CoV-2 | es_ES |
dc.subject | Oral cavity | es_ES |
dc.subject | Mouthrinse | es_ES |
dc.subject | β-cyclodextrins | es_ES |
dc.subject | Citrox | es_ES |
dc.subject | Viral load | es_ES |
dc.subject | Microbiome | es_ES |
dc.title | COVID-19: A Recommendation to Examine the Effect of Mouthrinses with β-Cyclodextrin Combined with Citrox in Preventing Infection and Progression | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.identifier.doi | doi:10.3390/jcm9041126 |