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dc.contributor.authorMartínez Téllez, Borja Manuel 
dc.contributor.authorGarcía Rivero, Yolanda
dc.contributor.authorSánchez-Delgado, Guillermo
dc.contributor.authorXu, Huiwen 
dc.contributor.authorAmaro Gahete, Francisco José 
dc.contributor.authorAcosta Manzano, Francisco Miguel
dc.contributor.authorRensen, Patrick C. N.
dc.contributor.authorBoon, Mariëtte R.
dc.contributor.authorLlamas Elvira, José Manuel 
dc.contributor.authorRuiz Ruiz, Jonatan
dc.identifier.citationB. Martinez-Tellez, et al. Supraclavicular skin temperature measured by iButtons and 18Ffluorodeoxyglucose uptake by brown adipose tissue in adults. Journal of Thermal Biology 82 (2019) 178–185 []es_ES
dc.descriptionThis study is part of a Ph.D. thesis conducted in the Biomedicine Doctoral Studies of the University of Granada, Spain.es_ES
dc.description.abstractCurrently, 18 [F]-Fluorodeoxyglucose (18F-FDG) in combination with a positron emission tomography/computed tomography (PET/CT) scan analysis is the most commonly used method to quantify human BAT volume and activity. However, this technique presents several drawbacks which negatively affect participant's health. The aim of the present work is to determine whether supraclavicular skin temperature can be used as an indirect marker of cold-induced BAT and skeletal muscle 18F-FDG uptake in adults, while taking into account body composition. We performed a personalized cooling protocol just before an 18F-FDG-PET/CT scan, and we measured supraclavicular skin temperature before (in warm conditions) and after the cooling protocol in 88 adults (n = 57 women, mean age: 21.9 ± 2.1 years old, body mass index: 24.5 ± 4.3 km/m2). We found that supraclavicular skin temperature at the warm and cold periods was weakly and positively associated with BAT activity (SUVmean and SUVpeak: β = 3.000; R2 = 0.072; P = 0.022 and β = 2.448; R2 = 0.060; P = 0.021), but not with skeletal muscle 18F-FDG uptake, after controlling for body composition. We performed further analyses and the positive associations persisted only in the group of women. In conclusion, supraclavicular skin temperature in warm and cold conditions seems to be related with cold-induced 18F-FDG uptake by BAT only in women, although the low explained variance of these associations means that there are other factors involved in the supraclavicular skin temperature.es_ES
dc.description.sponsorshipThis study was supported by the Spanish Ministry of Economy and Competitiveness, Fondo de Investigación Sanitaria del Instituto de Salud Carlos III (PI13/01393) and Retos de la Sociedad (DEP2016-79512-R), Fondos Estructurales de la Unión Europea (FEDER), by the Spanish Ministry of Education (FPU 13/04365, 14/04172, and 16/05159), by the Fundación Iberoamericana de Nutrición (FINUT), by the Redes temáticas de investigación cooperativa RETIC (Red SAMID RD16/0022), by AstraZeneca HealthCare Foundation and by the University of Granada Plan Propio de Investigación 2016 -Excellence actions: Unit of Excellence on Exercise and Health (UCEES) - and Plan Propio de Investigación 2018 - Programa Contratos-Puente, and the Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades (FEDER: ref. SOMM17/6107/UGR).es_ES
dc.rightsAtribución 3.0 España*
dc.subjectBrown fates_ES
dc.titleSupraclavicular skin temperature measured by iButtons and 18Ffluorodeoxyglucose uptake by brown adipose tissue in adultses_ES

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Atribución 3.0 España
Except where otherwise noted, this item's license is described as Atribución 3.0 España