Metabolic Syndrome and Its Associated Early-Life Factors among Chinese and Spanish Adolescents: A Pilot Study
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AuthorWang, Jiao; Perona, Javier S.; Schmidt Río Valle, Jacqueline; Chen, Yajun; Jing, Jin; González Jiménez, Emilio
Metabolic syndromeBreastfeeding durationBirth weightAdolescents
Wang, J., Perona, J. S., Schmidt-RioValle, J., Chen, Y., Jing, J., & González-Jiménez, E. (2019). Metabolic Syndrome and Its Associated Early-Life Factors among Chinese and Spanish Adolescents: A Pilot Study. Nutrients, 11(7), 1568.
SponsorshipThe research conducted in Spain was funded by the Spanish Interministerial Commission of Science and Technology (CYCIT, AGL2011-23810). The research in China was funded by the National Natural Science Foundation of China (grant number 81673193) as well as by a special research grant for nonprofit public service of the Ministry of Health of China (grant number 201202010).
Metabolic syndrome (MetS) is a growing problem worldwide in adolescents. This study compared two sample populations of young people in Spain and China, and analyzed the association of birth weight and breastfeeding duration with MetS. A cross-sectional study was conducted in adolescents (10–15 years old); 1150 Chinese and 976 Spanish adolescents. The variables analyzed were anthropometric characteristics, biochemical markers, and demographic characteristics using the same methodology and data collection protocol. Also, birth weight and breastfeeding were retrospectively analyzed during the first year of life. The results showed statistically significant di erences between the two groups in reference to body mass index (BMI), blood pressure, triglyceride, glucose, and high-density lipoprotein cholesterol (HDL-C) levels. The MetS prevalence was higher in Spanish adolescents (2.5%) than in the Chinese group (0.5%). Breastfeeding duration was inversely associated with hypertriglyceridemia, low HDL-C, and MetS, whereas higher birth weight was associated with hyperglycemia, low HDL-C, hypertriglyceridemia, and abdominal obesity. Spanish adolescents showed more altered MetS components, and consequently, a higher MetS prevalence than the Chinese adolescents. This made them more vulnerable to cardiometabolic risk. Our results highlight the need for interventions designed by health professionals, which would encourage pregnant women to breastfeed their children.