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Association Between the Use of a Mobile Health Strategy App and Biological Changes in Breast Cancer Survivors: Prospective Pre-Post Study
dc.contributor.author | Lozano Lozano, Mario | |
dc.contributor.author | Melguizo Rodríguez, Lucía Raquel | |
dc.contributor.author | Fernández Lao, Carolina | |
dc.contributor.author | Galiano Castillo, Noelia | |
dc.contributor.author | Cantarero Villanueva, Irene | |
dc.contributor.author | Martín Martín, Lydia María | |
dc.contributor.author | Arroyo Morales, Manuel | |
dc.date.accessioned | 2020-04-22T11:44:10Z | |
dc.date.available | 2020-04-22T11:44:10Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | Lozano-Lozano, M., Melguizo-Rodríguez, L., Fernández-Lao, C., Galiano-Castillo, N., Cantarero-Villanueva, I., Martín-Martín, L., & Arroyo-Morales, M. (2019). Association Between the Use of a Mobile Health Strategy App and Biological Changes in Breast Cancer Survivors: Prospective Pre-Post Study. Journal of medical Internet research, 21(8), e15062. | es_ES |
dc.identifier.uri | http://hdl.handle.net/10481/61483 | |
dc.description.abstract | The objectives of this study were to: (1) check whether it is feasible to find changes in inflammation biomarkers through an mHealth strategy app as a delivery mechanism of an intervention to monitor energy balance; and (2) discover potential predictors of change of these markers in breast cancer survivors (BCSs). Analyzing changes in inflammatory biomarker concentrations after using the mHealth app, differences between preassessment CRP (4899.04 pg/ml; SD 1085.25) and IL-6 (87.15 pg/ml; SD 33.59) and postassessment CRP (4221.24 pg/ml; SD 911.55) and IL-6 (60.53 pg/ml; SD 36.31) showed a significant decrease in both markers, with a mean difference of –635.25 pg/ml (95% CI –935.65 to –334.85; P<.001) in CRP and –26.61 pg/ml (95% CI –42.51 to –10.71; P=.002) in IL-6. Stepwise regression analyses revealed that changes in global quality of life, as well as uMARS score and hormonal therapy, were possible predictors of change in CRP concentration after using the mHealth app. In the same way, the type of tumor removal surgery conducted, as well as changes in weight and pain score, were possible predictors of change in IL-6 concentration after using the app. In conclusion, through the results of this study, we hypothesize that there is a possible association between an mHealth energy balance monitoring strategy and biological changes in BCSs. These changes could be explained by different biopsychosocial parameters, such as the use of the application itself, quality of life, pain, type of tumor removal surgery, hormonal treatment or obesity. | es_ES |
dc.description.sponsorship | The study was funded by the Spanish Ministry of Economy and Competitiveness (Plan Estatal de I+D+I 2013-2016), Fondo de Investigación Sanitaria del Instituto de Salud Carlos III (PI14/01627), Fondos Estructurales de la Unión Europea (FEDER), and by the Spanish Ministry of Education (FPU14/01069 and FPU17/00939). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | JMIR Publications, Inc | es_ES |
dc.rights | Atribución 3.0 España | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.subject | mHealth | es_ES |
dc.subject | C-reactive protein | es_ES |
dc.subject | Low-grade inflammatory | es_ES |
dc.title | Association Between the Use of a Mobile Health Strategy App and Biological Changes in Breast Cancer Survivors: Prospective Pre-Post Study | es_ES |
dc.type | journal article | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.identifier.doi | 10.2196/15062 |