Show simple item record

dc.contributor.authorTorres, Marta
dc.contributor.authorHong, Kar-Wai
dc.contributor.authorChong, Teik-Min
dc.contributor.authorReina, José Carlos
dc.contributor.authorChan, Kok-Gan
dc.contributor.authorDessaux, Yves
dc.contributor.authorLlamas Company, Inmaculada
dc.identifier.citationTorres, M., Hong, K. W., Chong, T. M., Reina, J. C., Chan, K. G., Dessaux, Y., & Llamas, I. (2019). Genomic analyses of two Alteromonas stellipolaris strains reveal traits with potential biotechnological applications. Scientific reports, 9(1), 1-14.es_ES
dc.description.abstractThe Alteromonas stellipolaris strains PQQ-42 and PQQ-44, previously isolated from a fish hatchery, have been selected on the basis of their strong quorum quenching (QQ) activity, as well as their ability to reduce Vibrio-induced mortality on the coral Oculina patagonica. In this study, the genome sequences of both strains were determined and analyzed in order to identify the mechanism responsible for QQ activity. Both PQQ-42 and PQQ-44 were found to degrade a wide range of N-acylhomoserine lactone (AHL) QS signals, possibly due to the presence of an aac gene which encodes an AHL amidohydrolase. In addition, the different colony morphologies exhibited by the strains could be related to the differences observed in genes encoding cell wall biosynthesis and exopolysaccharide (EPS) production. The PQQ-42 strain produces more EPS (0.36 g l−1) than the PQQ-44 strain (0.15 g l−1), whose chemical compositions also differ. Remarkably, PQQ-44 EPS contains large amounts of fucose, a sugar used in high-value biotechnological applications. Furthermore, the genome of strain PQQ-42 contained a large nonribosomal peptide synthase (NRPS) cluster with a previously unknown genetic structure. The synthesis of enzymes and other bioactive compounds were also identified, indicating that PQQ-42 and PQQ-44 could have biotechnological applications.es_ES
dc.description.sponsorshipI.L. was supported by a Spanish Ministry of Economy, Industry and Competitiveness research project (AGL2015- 68806-R); Y.D. by an annual grant from the French National Scientific Research Center (CNRS); Y.D. and K.G.C. by the French Embassy in Malaysia and K.G.C. by the University of Malaysia (grants H-50001-A000027 and GA001-2016). The Institute for Integrative Biology of the Cell also received support from the LabEx Saclay Plant Sciences-SPS (ANR-10-LABX-0040-SPS). M.T. was supported by an FPU Fellowship (FPU13-0466) and the International Mobility Programme (EST15/00709) of the Spanish Ministry of Science and Education. K.W.H. and T.M.C. received grants from the French Embassy in Malaysia. J.C.R. was supported by an FPU Fellowship grant (FPU15-01717).es_ES
dc.publisherSpringer Naturees_ES
dc.rightsAtribución 3.0 España*
dc.titleGenomic analyses of two Alteromonas stellipolaris strains reveal traits with potential biotechnological applicationses_ES

Files in this item


This item appears in the following Collection(s)

Show simple item record

Atribución 3.0 España
Except where otherwise noted, this item's license is described as Atribución 3.0 España