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dc.contributor.authorde la Visitación, Néstor
dc.contributor.authorRobles-Vera, Iñaki
dc.contributor.authorToral Jiménez, Marta
dc.contributor.authorDuarte Pérez, Juan Manuel
dc.identifier.citationde la Visitación, N., Robles-Vera, I., Toral, M., & Duarte, J. (2019). Protective Effects of Probiotic Consumption in Cardiovascular Disease in Systemic Lupus Erythematosus. Nutrients, 11(11), 2676.es_ES
dc.description.abstractThe prevalence of renal and cardiovascular disease (CVD) in patients with systemic lupus erythematosus (SLE) is higher than in general populations. Recently, a causal role of gut microbiota on the development of immune responses in SLE has been described. Probiotic consumption changes the composition of gut microbiota, preventing SLE progression. The aim of this review is to explore the role of the gut microbiota in the development of renal and cardiovascular disease in SLE and how probiotics could be a therapeutic option. Despite strong evidence on the beneficial effects of probiotics in the development of autoimmunity and nephritis in SLE, only a few studies described the protective effects of Lactobacillus in important risk factors for CVD, such as endothelial dysfunction and hypertension in mice. The preventive effects of probiotics in renal and CVD in humans have not been established yet.es_ES
dc.description.sponsorshipThis work was supported by grants from Comisión Interministerial de Ciencia y Tecnología, Ministerio de Economía y competitividad (MINECO) (SAF2014-55523-R, SAF2017-84894-R) and Junta de Andalucía (Proyecto de excelencia P12-CTS-2722, and CTS 164), with funds from the European Union, and by the Ministerio de Economia y Competitividad, Instituto de Salud Carlos III (CIBER-CV). I.R.-V. is a predoctoral fellow of MINECO; N.d.l.V. is a predoctoral fellow of Junta de Andalucía and Fondo Social Europeo “FEDER una manera de hacer Europa”, and M.T. is a postdoctoral fellow of Instituto de Salud Carlos III (Sara Borrell Program).es_ES
dc.rightsAtribución 3.0 España*
dc.subjectImmune responsees_ES
dc.subjectGut microbiotaes_ES
dc.subjectEndothelial dysfunctiones_ES
dc.subjectHypertension es_ES
dc.titleProtective Effects of Probiotic Consumption in Cardiovascular Disease in Systemic Lupus Erythematosuses_ES

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Atribución 3.0 España
Except where otherwise noted, this item's license is described as Atribución 3.0 España