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dc.contributor.authorRíos Ruiz, Francisco 
dc.contributor.authorAlberola, Antonio
dc.contributor.authorMeléndez, Joaquín
dc.contributor.authorMuedra, Gema
dc.contributor.authorTrigo, Francisco
dc.date.accessioned2019-12-17T13:22:01Z
dc.date.available2019-12-17T13:22:01Z
dc.date.issued2017-02-10
dc.identifier.citationRíos, F.; Alberola, A.; Melendez, J.; Muedra, G.; Trigo, F. A Validated HPLC Method for the Determination of Vanillyl Butyl Ether in Cosmetic Preparations. Cosmetics 2017, 4, 9. [doi:10.3390/cosmetics4010009]es_ES
dc.identifier.urihttp://hdl.handle.net/10481/58383
dc.description.abstractA specific HPLC (High-Performance Liquid Chromatography) method has been developed and validated for the determination of vanillyl butyl ether in cosmetic products. The extraction procedure with an isopropanol water 1:1 mixture is described. The method uses a RP-C-18 column with isocratic elution and an ultraviolet (UV) detector. The mobile phase consists of a mixture of acetonitrile and buffer (Na2HPO4 20 mM in water) (30:70 v/v) with a variable flow rate. The method was validated with respect to accuracy, precision (repeatability and reproducibility), specificity and linearity. The procedure described here is simple, selective and reliable for routine quality control analysis and stability tests of commercially available cosmetic products.es_ES
dc.description.sponsorshipFrancisco Ríos acknowledges the support fromthe Spanish Ministry of Economy, Industry and Competitiveness within the postdoctoral grant “Ayudas para contratos Torres Quevedo” (PTQ-15-07879).es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsAtribución 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectVanillyl butyl etheres_ES
dc.subjectHPLCes_ES
dc.subjectMethod validationes_ES
dc.subjectCosmetic productes_ES
dc.titleA Validated HPLC Method for the Determination of Vanillyl Butyl Ether in Cosmetic Preparationses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES
dc.identifier.doi10.3390/cosmetics4010009


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Atribución 3.0 España
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