Genetic polymorphisms associated to obesity and cardiovascular disease risk factors in European adolescents
Metadata
Show full item recordAuthor
Pascual Gamarra, José MiguelEditorial
Universidad de Granada
Departamento
Universidad de Granada. Programa de Doctorado en BiomedicinaMateria
Genetic polymorphisms Obesity Cardiovascular disease risk European adolescents
Date
2019Fecha lectura
2019-10-11Referencia bibliográfica
Pascual Gamarra, José Miguel. Genetic polymorphisms associated to obesity and cardiovascular disease risk factors in European adolescents. Granada: Universidad de Granada, 2019. [http://hdl.handle.net/10481/57451]
Sponsorship
Tesis Univ. Granada.; The financial support of the European Community (FP6-2003-Food-2-A, FOOD-CT-2005 007034). The Spanish Ministry of Education (FPU16/02127).Abstract
Obesity and related
cardiovascular diseases (CVDs)
are the main cause of premature
death and chronic disability
worldwide. CVD events occur
most frequently during or after
the fifth decade of life, however,
there is evidence indicating that
the precursors of CVD have its
origin in the first decades of life.
Therefore, prevention is
fundamental to reduce the
incidence of these pathologies,
especially in young people. CVDs
are a result of complex
interactions between
environmental and genetic risk
factors.
The overall aim of the present
Doctoral Thesis was to study the
genetics variants of Uncoupling
proteins (UCP), cilliary
neurotrophic factor (CNTF),
lipoprotein lipase (LPL) and
adiponectin (ADIPOQ) genes
associated to obesity and others
CVD risk factors in adolescents
and the potential interaction
with physical activity (PA).