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Automated Detection and Segmentation of Nonmass-Enhancing Breast Tumors with Dynamic Contrast-Enhanced Magnetic Resonance Imaging
dc.contributor.author | Álvarez Illán, Ignacio | |
dc.contributor.author | Ramírez Pérez De Inestrosa, Javier | |
dc.contributor.author | Gorriz Sáez, Juan Manuel | |
dc.contributor.author | Marino, Maria Adele | |
dc.contributor.author | Avendano, Daly | |
dc.contributor.author | Helbich, Thomas | |
dc.contributor.author | Baltzer, Pascal | |
dc.contributor.author | Pinker, Katja | |
dc.contributor.author | Meyer-Baese, Anke | |
dc.date.accessioned | 2019-10-09T12:03:27Z | |
dc.date.available | 2019-10-09T12:03:27Z | |
dc.date.issued | 2018-10-24 | |
dc.identifier.citation | Illan, I. A., Ramirez, J., Gorriz, J. M., Marino, M. A., Avendano, D., Helbich, T., ... & Meyer-Baese, A. (2018). Automated Detection and Segmentation of Nonmass-Enhancing Breast Tumors with Dynamic Contrast-Enhanced Magnetic Resonance Imaging. Contrast media & molecular imaging, 2018. | es_ES |
dc.identifier.uri | http://hdl.handle.net/10481/57274 | |
dc.description.abstract | Nonmass-enhancing (NME) lesions constitute a diagnostic challenge in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of the breast. Computer-aided diagnosis (CAD) systems provide physicians with advanced tools for analysis, assessment, and evaluation that have a significant impact on the diagnostic performance. Here, we propose a new approach to address the challenge of NME lesion detection and segmentation, taking advantage of independent component analysis (ICA) to extract data-driven dynamic lesion characterizations. A set of independent sources was obtained from the DCE-MRI dataset of breast cancer patients, and the dynamic behavior of the different tissues was described by multiple dynamic curves, together with a set of eigenimages describing the scores for each voxel. A new test image is projected onto the independent source space using the unmixing matrix, and each voxel is classified by a support vector machine (SVM) that has already been trained with manually delineated data. A solution to the high false-positive rate problem is proposed by controlling the SVM hyperplane location, outperforming previously published approaches. | es_ES |
dc.description.sponsorship | European Unions Horizon 2020 Research and Innovation Programme under the Marie Skodowska-Curie grant agreement No. 656886 | es_ES |
dc.description.sponsorship | Austrian National Bank "Jubilaeumsfond" Project 16219 | es_ES |
dc.description.sponsorship | 2020-Research and Innovation Framework Programme PHC-11-2015 667211-2 | es_ES |
dc.description.sponsorship | Siemens Austria | es_ES |
dc.description.sponsorship | Novomed | es_ES |
dc.description.sponsorship | Guerbet, France | es_ES |
dc.description.sponsorship | NIH/NCI Cancer Center Support Grant P30CA008748 | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | CONTRAST MEDIA & MOLECULAR IMAGING | es_ES |
dc.relation | 656886 | es_ES |
dc.relation | 667211-2 | es_ES |
dc.rights | Atribución 3.0 España | * |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | * |
dc.subject | COMPUTER-AIDED DIAGNOSIS | es_ES |
dc.subject | DCE-MRI DATA | es_ES |
dc.subject | LESION SEGMENTATION | es_ES |
dc.subject | COMPONENT ANALYSIS | es_ES |
dc.subject | Cáncer | es_ES |
dc.title | Automated Detection and Segmentation of Nonmass-Enhancing Breast Tumors with Dynamic Contrast-Enhanced Magnetic Resonance Imaging | es_ES |
dc.type | journal article | es_ES |
dc.rights.accessRights | open access | es_ES |
dc.identifier.doi | 10.1155/2018/5308517 |