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dc.contributor.authorOlmedo Requena, María Rocío 
dc.contributor.authorGómez-Fernández, Julia
dc.contributor.authorAmezcua Prieto, María Del Carmen 
dc.contributor.authorMozas Moreno, Juan 
dc.contributor.authorSaeed Khan, Khalid 
dc.contributor.authorJiménez Moleón, José Juan
dc.identifier.citationOlmedo-Requena, R. [et al}. Pre-Pregnancy Adherence to the Mediterranean Diet and Gestational Diabetes Mellitus: A Case-Control Study. Nutrients 2019, 11, 1003; doi:10.3390/nu11051003.es_ES
dc.description.abstractGestational diabetes mellitus (GDM), an important public health problem that affects mothers and offspring, is a common metabolic disorder. We evaluated the effect of the pre-pregnancy Mediterranean diet (MD) level of exposure on the odds of GDM development. A case-control study (291 GDM cases and 1175 controls without GDM) was conducted in pregnant women. Pre-pregnancy dietary intake was assessed using a validated food frequency questionnaire to calculate an MD adherence index (range score 0–9: low ≤ 2; middle 3–4; high 5–6; very high ≥ 7). Adjusted odds ratios (aOR) and their 95% confidence intervals (CI) were estimated using multivariable logistic regression models including age, BMI, family history of diabetes mellitus, previous GDM, miscarriages, and gravidity. Overall, middle-high MD adherence was 216/291 (74.2%) and very high adherence was 17/291 (5.8%) in cases. In controls the corresponding figures were 900/1175 (76.6%) and 73/1175 (6.2%), respectively. Compared to low adherence, high MD adherence was associated with GDM reduction (aOR 0.61, 95% CI 0.39,0.94; p = 0.028), and very high MD adherence was even more strongly associated (aOR 0.33, 95% CI 0.15, 0.72; p = 0.005). The protective effect of adherence to the MD prior to pregnancy should be considered as a preventive tool against the development of GDM.es_ES
dc.rightsAtribución 3.0 España*
dc.subjectMediterranean diet (MD)es_ES
dc.subjectGestational diabetes mellitus (GDM)es_ES
dc.subjectPregnancy es_ES
dc.subjectMaternal nutritiones_ES
dc.subjectLifestyles es_ES
dc.titlePre-Pregnancy Adherence to the Mediterranean Diet and Gestational Diabetes Mellitus: A Case-Control Studyes_ES

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Atribución 3.0 España
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