Mostrar el registro sencillo del ítem

dc.contributor.authorMuñoz-Garach, Araceli
dc.contributor.authorGarcía Fontana, Beatriz 
dc.contributor.authorMuñoz Torres, Manuel Eduardo 
dc.date.accessioned2019-05-18T21:57:19Z
dc.date.available2019-05-18T21:57:19Z
dc.date.issued2019-03-16
dc.identifier.citationMuñoz-Garach, A.; García Fontana, B.; Muñoz-Torres, M. Vitamin D Status, Calcium Intake and Risk of Developing Type 2 Diabetes: An Unresolved Issue. Nutrients 2019, 11, 642; doi:10.3390/nu11030642.es_ES
dc.identifier.issn2072-6643
dc.identifier.urihttp://hdl.handle.net/10481/55766
dc.description.abstractThe relationship between vitamin D status, calcium intake and the risk of developing type 2 diabetes (T2D) is a topic of growing interest. One of the most interesting non-skeletal functions of vitamin D is its potential role in glucose homeostasis. This possible association is related to the secretion of insulin by pancreatic beta cells, insulin resistance in different tissues and its influence on systemic inflammation. However, despite multiple observational studies and several meta-analyses that have shown a positive association between circulating 25-hydroxyvitamin D concentrations and the risk of T2D, no randomized clinical trials supplementing with different doses of vitamin D have confirmed this hypothesis definitively. An important question is the identification of what 25-hydroxyvitamin D levels are necessary to influence glycemic homeostasis and the risk of developing T2D. These values of vitamin D can be significantly higher than vitamin D levels required for bone health, but the currently available data do not allow us to answer this question adequately. Furthermore, a large number of observational studies show that dairy consumption is linked to a lower risk of T2D, but the components responsible for this relationship are not well established. Therefore, the importance of calcium intake in the risk of developing T2D has not yet been established. Although there is a biological plausibility linking the status of vitamin D and calcium intake with the risk of T2D, well-designed randomized clinical trials are necessary to answer this important question.es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsAtribución 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectCalcium intakees_ES
dc.subjectDairy products es_ES
dc.subjectVitamin D es_ES
dc.subjectType 2 diabeteses_ES
dc.titleVitamin D Status, Calcium Intake and Risk of Developing Type 2 Diabetes: An Unresolved Issuees_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


Ficheros en el ítem

[PDF]

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

Atribución 3.0 España
Excepto si se señala otra cosa, la licencia del ítem se describe como Atribución 3.0 España