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dc.contributor.authorMelguizo Rodríguez, Lucía Raquel 
dc.contributor.authorRamos-Torrecillas, Javier
dc.contributor.authorManzano Moreno, Francisco Javier
dc.contributor.authorIllescas Montes, Rebeca 
dc.contributor.authorRivas, Ana
dc.contributor.authorRuiz Rodríguez, Concepción 
dc.contributor.authorLuna Bertos, María Elvira De 
dc.contributor.authorGarcía-Martínez, Olga
dc.identifier.citationMelguizo-RodrõÂguez L, Ramos-Torrecillas J, Manzano-Moreno FJ, Illescas-Montes R, Rivas A, Ruiz C, et al. (2018) Effect of phenolic extracts from different extra-virgin olive oil varieties on osteoblast-like cells. PLoS ONE 13(4). []es_ES
dc.description.abstractThe reported incidence of osteoporosis is lower in countries in which the Mediterranean diet predominates, and this apparent relationship may be mediated by the phenolic compounds present in olive oil. The objective of this study was to determine the effect of phenolic extracts from different varieties of extra-virgin olive oil (Picual, Arbequina, Picudo, and Hojiblanca) on the differentiation, antigenic expression, and phagocytic capacity of osteoblastlike MG-63 cells. At 24 h of treatment a significant increase in phosphatase alkaline activity and significant reductions in CD54, CD80, and HLA-DR expression and in phagocytic activity were observed in comparison to untreated controls. The in vitro study performed has demonstrated that phenolic compounds from different extra virgin olive oil varieties can modulate different parameters related to osteoblast differentiation and function.es_ES
dc.description.sponsorshipThis study was supported by the Ministerio de EducacioÂn, Cultura y Deporte (https:// mecd/catalogo/general/educacion/998758/ficha/ 998758-2015#dr[5]) grant FPU15-05635 to LucõÂa Melguizo-RodrõÂguez, the research group BIO277 (Junta de AndalucõÂa) and Department of Nursing.es_ES
dc.publisherCalogero Caruso, University of Palermo, ITALYes_ES
dc.rightsAtribución-NoComercial 3.0 España*
dc.titleEffect of phenolic extracts from different extra-virgin olive oil varieties on osteoblastlike cellses_ES

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Atribución-NoComercial 3.0 España
Except where otherwise noted, this item's license is described as Atribución-NoComercial 3.0 España