Association of cardiovascular emerging risk factors with acute coronary syndrome and stroke: A case-control study
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Martínez Linares, José Manuel; Guisado Barrilao, Rafael; Ocaña Peinado, Francisco; Salgado Parreño, Francisco JavierEditorial
Wiley-Blackwell Publishing Asia
Materia
Acute coronary syndrome Cardiovascular disease Case-control study Risk factor Stroke
Date
2016-12-01Referencia bibliográfica
Martínez Linares, J.M.; et al. Association of cardiovascular emerging risk factors with acute coronary syndrome and stroke: A case control study [pre-print]. Nursing and Health Sciences, 18(4): 488-495 (2016). [http://hdl.handle.net/10481/47969]
Sponsorship
Health Agency of Health South of Granada.; Project from "Ministerio de Economía y Competitividad. Dirección General de Investigación Científica y Técnica". Grant Number: MTM2013-47929-PAbstract
In this study, we estimated the risk of acute coronary syndrome and stroke associated with several emerging
cardiovascular risk factors. This was a case-control study, where an age - and sex-matched acute coronary
syndrome group and stroke group were compared with controls. Demographic and clinical data were collected
through patient interviews, and blood samples were taken for analysis. In the bivariate analysis, all cardiovascular
risk factors analyzed showed as predictors of acute coronary syndrome and stroke, except total cholesterol and
smoking. In the multivariate logistic regression model for acute coronary syndrome, hypertension and body mass
index, N-terminal section brain natriuretic peptide and pregnancy-associated plasma protein-Awere independent
predictors. For stroke, the predictors were hypertension, diabetes mellitus, body mass index, and N-terminal
section brain natriuretic peptide. Controlling for age, sex, and classical cardiovascular risk factors, N-terminal
section brain natriuretic peptide and pregnancy-associated plasma protein-A were independent emerging
cardiovascular risk factors for acute coronary syndrome, but pregnancy-associated plasma protein-A was not
for stroke. High levels of cardiovascular risk factors in individuals with no episodes of cardiovascular disease
requires the implementation of prevention programs, given that at least half of them are modifiable.