Evaluation of the anti-wrinkle efficacy of cosmetic formulations with an anti-aging peptide (Argireline®).
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AuthorRuiz Martínez, María A.; Clares Naveros, Beatriz; Morales Hernández, María Encarnación; Gallardo Lara, Visitación
Universidad de Granada, Facultad de Farmacia
Botox effectArgireline®Acetyl hexapeptide-8Anti-Wrinkling Efficacy
Ruiz Martínez, M.A.;[et. al]. Evaluation of the anti-wrinkle efficacy of cosmetic formulations with an anti-aging peptide (Argireline®). Ars Pharm, 2010, Vol.50 nº 4; 168-176.[http://hdl.handle.net/10481/27392]
The purpose of this research was to evaluate, by means of in vivo studies, the efficacy of new cosmetic active ingredients which effect of botox, called Argireline®), so that width and depth of wrinkles could be established. For this, it is prepared two formulations: an emulsion with an external aqueous phase for normal to dry skin, and a gel for oily skin. We likewise study the water content of the skin after the application of both formulas, as this must be one of the priority functions of facial treatments in general, as well as the level of satisfaction from the subjective point of view, fundamental for patients and their continuation of the treatment. After the designed tests, it is possible to verify that there is a remarkable diminution of the wrinkles size tested in each patient during the month of treatment. Besides, it is possible to review how the moisturizing capacity has been increased in all cases. At the end of the visual test, all the volunteers experienced a reduction in the depth of wrinkles, and from the subjective point of view, the appearance and elasticity of the skin were improved. Finally it is possible to conclude that Argireline® (acetyl hexapeptide-8 ) shows a great antiaging capacity in all the cases that have been studied and the tried compounds have increased moisturizing power.