Grupo: Promoting Fitness and Health Through Physical Activity (CTS977)

METABOLIZATP: Un Serious Game como recurso educativo para comprender el metabolismo anaeróbico aláctico

METABOLIZATP: Un Serious Game como recurso educativo para comprender el metabolismo anaeróbico aláctico Herrador Colmenero, Manuel

Manual of Procedures Summary of FLADEX project

Manual of Procedures Summary of FLADEX project Esteban Cornejo, Irene; Martin-Fuentes, Isabel; Solís Urra, Patricio; Fernandez-Gamez, Beatriz; Toval, Angel; Caro-Rus, Alfredo; Coca-Pulido, Andrea; Olvera-Rojas, Marcos; Sanchez-Martinez, Javier; Fernández‐Ortega, Javier; Bellón, Darío; Sánchez-Aranda, Lucía; Sclafani, Alessandro; Marín-Álvarez, José David; Barranco-Moreno, Emilio José; Gómez Río, Manuel; Rodríguez-Palacios, María Teresa Alzheimer's disease (AD) is one of the leading causes of disability worldwide. Alterations in cerebral blood flow (CBF) and blood biomarkers of AD are critical in the early stages of the disease. Exercise is a promising non-pharmaceutical intervention to reverse these physiological changes, but the specific mechanisms by which exercise improves brain health remain unknown. The flADex project aims to examine the acute effects of different types of exercise on CBF and blood biomarkers of AD in cognitively normal older adults. FlADex is a counterbalanced crossover trial that will enroll 20 adults aged 68 to 83 years with negative brain amyloid status (<12 centiloid) who are non-carriers of APOE e4. All participants will complete a 30-minute session of each condition in a randomized order: (i) moderate-intensity aerobic exercise (60–70% of maximum heart rate), (ii) moderate- intensity resistance exercise (perceived exertion rating: 4–6 points out of 10), and (iii) resting condition. The primary outcome, CBF, will be assessed using magnetic resonance imaging at baseline and at three post-condition time points (starting at 20, 27, and 34 minutes). Blood biomarkers of AD (Aβ42, Aβ40, p-tau217, p-tau181, GFAP, NfL) and growth factors (BDNF, IGF-1) will be measured before and after each condition (at 3, 50, and 70 minutes). Cognitive outcomes (sequential image memory and Flanker tests) and mood (POMS questionnaire and Feeling Scale) will be measured before and after the condition. This document provides an index of the chapters detailing each of the manuals of procedures implemented in the flADex Project. The objective of publishing the flADex manuals of procedures is to enhance the visibility of the procedures conducted across all phases of the project and to make them openly accessible for consultation by anyone interested.

Impact of social marketing in the prevention of childhood obesity

Impact of social marketing in the prevention of childhood obesity Gracia Marco, Luis Andrés; Moreno, Luis A; Vicente-Rodríguez, Germán Obesity, mainly childhood obesity, is a worldwide concern. Childhood obesity continues to adulthood, and it is associated with multiple noncommunicable diseases. One important aspect in the fight against obesity is prevention, the earlier, the better. Social marketing is a novel concept being increasingly used as an approach to address social problems and more and more included in the community-based interventions aiming to change unhealthy behaviors. Although there is limited evidence of its effectiveness, it seems that when conscientiously applied, social marketing principles may be useful to change behaviors and thus better health outcomes.

Socioeconomic status and bone mass in Spanish adolescents. The HELENA Study

Socioeconomic status and bone mass in Spanish adolescents. The HELENA Study Gracia Marco, Luis Andrés; Ortega Porcel, Francisco Bartolomé; Casajús, José A; Sioen, Isabelle; Widhalm, Kurt; Béghin, Laurent; Vicente-Rodríguez, Germán; Moreno, Luis A Purpose: Socioeconomic status (SES) has been frequently associated with body composition, particularly fat mass and obesity. However, the SES-bone mass association is not clear. We aimed to evaluate the associations between different SES indicators (Family Affluence Scale, parental education, and occupation) and bone mineral content in Spanish adolescents. Methods: Participants were 322 adolescents (164 boys and 158 girls, 12.5-17.5 years) from the Healthy Lifestyle in Europe by Nutrition in Adolescence study. The social background of the adolescents was self-reported using an SES questionnaire, and the bone variables were measured using dual-energy x-ray absorptiometry. Physical activity was measured using accelerometers. Calcium intake was estimated from two nonconsecutive 24 hours recalls. One-way analysis of covariance was performed to examine the relationships between SES indicators and bone mass using different sets of confounders: basic model (sex + sexual maturation), model 1 (basic model + height), model 2 (basic model + lean mass), and model 3 (basic model + calcium intake + average physical activity). Results: Adjusted results showed no association between SES indicators and whole-body or total hip bone mineral content. Additional analyses were performed in lumbar spine, pelvis, and hip subregions (femoral neck, trochanter, and intertrochanter), and no significant associations were observed at these sites either. Conclusions: Our data do not support a link between different SES indicators (Family Affluence Scale, parental education, and occupation) and bone mass in adolescents.

Sedentary behaviours and its association with bone mass in adolescents: the HELENA Cross-Sectional Study

Sedentary behaviours and its association with bone mass in adolescents: the HELENA Cross-Sectional Study Gracia Marco, Luis Andrés; Rey-López, Juan P; Santaliestra-Pasías, Alba María; Jiménez Pavón, David; Díaz, Ligia E; Moreno, Luis A; Vicente-Rodríguez, German Background: We aimed to examine whether time spent on different sedentary behaviours is associated with bone mineral content (BMC) in adolescents, after controlling for relevant confounders such as lean mass and objectively measured physical activity (PA), and if so, whether extra-curricular participation in osteogenic sports could have a role in this association. Methods: Participants were 359 Spanish adolescents (12.5-17.5 yr, 178 boys,) from the HELENA-CSS (2006-07). Relationships of sedentary behaviours with bone variables were analysed by linear regression. The prevalence of low BMC (at least 1SD below the mean) and time spent on sedentary behaviours according to extracurricular sport participation was analysed by Chi-square tests. Results: In boys, the use of internet for non-study was negatively associated with whole body BMC after adjustment for lean mass and moderate to vigorous PA (MVPA). In girls, the time spent studying was negatively associated with femoral neck BMC. Additional adjustment for lean mass slightly reduced the negative association between time spent studying and femoral neck BMC. The additional adjustment for MVPA did not change the results at this site. The percentage of girls having low femoral neck BMC was significantly smaller in those participating in osteogenic sports (≥ 3 h/week) than in the rest, independently of the cut-off selected for the time spent studying. Conclusions: The use of internet for non-study (in boys) and the time spent studying (in girls) are negatively associated with whole body and femoral neck BMC, respectively. In addition, at least 3 h/week of extra-curricular osteogenic sports may help to counteract the negative association of time spent studying on bone health in girls.