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<title>APh, vol. 51(4)</title>
<link>https://hdl.handle.net/10481/24847</link>
<description/>
<pubDate>Sat, 11 Apr 2026 12:24:21 GMT</pubDate>
<dc:date>2026-04-11T12:24:21Z</dc:date>
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<title>El museo de la Historia de la Farmacia “Prof. José María Suñe Arbussá”</title>
<link>https://hdl.handle.net/10481/27362</link>
<description>El museo de la Historia de la Farmacia “Prof. José María Suñe Arbussá”
Martín Martín, Carmen; López Andújar, Guillermina
</description>
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<item>
<title>Aplicación de la filosofía “wiki” a la actualización del material docente en el área de farmacia y tecnología farmacéutica</title>
<link>https://hdl.handle.net/10481/27361</link>
<description>Aplicación de la filosofía “wiki” a la actualización del material docente en el área de farmacia y tecnología farmacéutica
González Rodríguez, M.L.; Ramos Carrillo, Antonio; Rabasco Álvarez, A.
La Directiva 2005/36/CE del Parlamento Europeo y del Consejo, relativa al reconocimiento de&#13;
cualificaciones profesionales, en su artículo 44, referente a la formación del farmacéutico, y la Orden&#13;
CIN/2137/2008, por la que se establecen los requisitos para la verificación de los títulos universitarios&#13;
oficiales que habiliten para el ejercicio de esta profesión, recogen conocimientos y competencias que&#13;
deben contemplarse en su formación académica. Muchos de ellos están directamente relacionados&#13;
con los fármacos y con los medicamentos y, por tanto, estrechamente vinculados con el Área de&#13;
Conocimiento de “Farmacia y Tecnología Farmacéutica”.&#13;
Como profesores de esta Área desde hace muchos años, hemos apreciado la dificultad existente en la&#13;
preparación del material docente. Este hecho es debido a diversas razones. Entre ellas destacan: a)&#13;
limitación de las fuentes documentales existentes sobre las propiedades físico-químicas y&#13;
biofarmacéuticas de muchos principios activos; b) escasez de textos concernientes a la fabricación&#13;
concreta de medicamentos; c) irrupción continua en el mercado de nuevos medicamentos, que implica&#13;
que muchos textos se queden desfasados; d) dispersión de los contenidos.&#13;
Para intentar soslayar esta problemática, se han venido realizando diversas actividades docentes. Una&#13;
de ellas, objeto de la presente comunicación, fue implantada en el curso 2009-10, para los alumnos de&#13;
5º curso y se seguirá incluyendo en la programación docente para el próximo 2010-11. Está basada en&#13;
el concepto “wiki”. Consiste en la elaboración, por parte de alumnos y profesores, de un espacio&#13;
común, convenientemente organizado, donde todos aportan información para elaborar una gran enciclopedia virtual sobre el medicamento.; Directive 2005/36/EC of the European Parliament and Council on the recognition of professional&#13;
qualifications, section 44, concerning the formation of pharmacists, and the Order CIN/2137/2008,&#13;
laying down the requirements for verification of official university degrees that prepare students to&#13;
work in this profession, gather knowledge and skills to be covered in their education. Many of them&#13;
are directly related to drugs and medicines and, therefore, closely linked to the Knowledge Area&#13;
"Pharmacy and Pharmaceutical Technology”.&#13;
As teachers of this area for many years, we have appreciated the difficulty in preparing the teaching&#13;
material. This is due to various reasons. These include: a) limitation of existing documentary sources&#13;
on the physico-chemical and biopharmaceutical characteristics of many active ingredients. b) a&#13;
shortage of texts concerning the specific manufacture of medicaments. c) continuous irruption in the&#13;
market for new drugs and dosage forms, which means that many texts become outdated. d)&#13;
information dispersion.&#13;
To circumvent this problem, various educational activities have being conducted. One of this, object of the present communication, was introduced in 2009-10 for students in the 5th grade and still be included in the course program for the next 2010-11. It is based on the concept of "wiki". It consists&#13;
of establishing, by students and teachers, a common area, conveniently organized in which all provide information to develop a virtual encyclopedia of medicaments.
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<item>
<title>Potential impact of European decisions and reports in pharmacy planning in Spain</title>
<link>https://hdl.handle.net/10481/27360</link>
<description>Potential impact of European decisions and reports in pharmacy planning in Spain
Moreno Plantada, Javier; Garrigues, T.M.; Martín Villodre, A.M.; Muelas, J.A.
Currently there are several cases in the field of the European Union regarding Spanish&#13;
legislation on private pharmacy planning. The first of these cases was initiated by issuing a&#13;
reasoned opinion by the European Commission on 28 June 2006. The second approach has&#13;
taken place through the various preliminary questions raised before the Court of Justice of&#13;
the European Communities by certain Spanish courts. Although not all of the above&#13;
procedures have been completed, certain European pronouncements do provide what might&#13;
be the consequences that they may have on the Spanish legislation on the subject. It is very&#13;
likely that the binomial property-ownership in favor of pharmacists and planning criteria&#13;
established in the Spanish regulations is considered compatible with European law. On the&#13;
contrary, it is feasible that certain aspects of the merit scales applied by the Autonomous&#13;
Communities for awarding newly authorized community pharmacies must be changed.
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<item>
<title>Comparative Investigation on in vitro release of extemporaneously prepared norfloxacin semisolid formulations with marketed silver sulfadiazine 1% cream, USP using model independent approach</title>
<link>https://hdl.handle.net/10481/27358</link>
<description>Comparative Investigation on in vitro release of extemporaneously prepared norfloxacin semisolid formulations with marketed silver sulfadiazine 1% cream, USP using model independent approach
Dua, Kamal; Pabreja, Kavita; Ramana, M.V.
Objective&#13;
In an attempt for better treatment of bacterial infections, various semisolid formulations containing 5%&#13;
w/w of norfloxacin were prepared and evaluated for in vitro drug release and in vitro skin permeability&#13;
using dialysis membrane and rat abdominal skin respectively. The in vitro diffusion and permeation&#13;
profile of the prepared formulation was compared with marketed silver sulfadiazine cream 1%, USP&#13;
using model independent approach.&#13;
Methods&#13;
Various semisolid formulations were prepared with different dermatological bases using&#13;
standard procedures. In vitro diffusion and permeation studies were carried out using Keshary-Chein&#13;
(KC) type diffusion cell using dialysis membrane and rat abdominal skin respectively.&#13;
Results&#13;
The f1 lower than 15 and f2 higher than 50 indicated similarities in the in vitro diffusion and&#13;
permeation profiles of the extemporaneously prepared selected semisolid formulations and marketed&#13;
silver sulfadiazine 1% cream, USP.&#13;
Conclusion&#13;
Amongst all the semisolid formulations prepared, carbopol gel base was found to be most suitable&#13;
dermatological base for norfloxacin, the results obtained for in vitro diffusion, and in vitro skin permeation studies are comparable with that of marketed silver sulphadiazine 1% cream, USP.
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<title>Antidiabetic and nephroprotective effect of tectona grandis linn. In alloxan induced diabetes</title>
<link>https://hdl.handle.net/10481/27352</link>
<description>Antidiabetic and nephroprotective effect of tectona grandis linn. In alloxan induced diabetes
Ghaisas, Mahesh M.; Navghare, V.V.; Takawale, A.R.; Zope, V.S.; Phanse, M.A.
In the present study, effect of ethanolic extract of bark of Tectona grandis Linn. (TG) was evaluated&#13;
using alloxan induced diabetes and associated renal complication. The diabetes was induced by&#13;
administration of alloxan to the rats at the dose of 140 mg/kg, i.p. TG was administered to diabetic&#13;
animals for six weeks and various biochemical parameters in blood and urine (plasma glucose, serum&#13;
albumin, total protein, and creatinine, urine total protein, urine albumin), tissue parameters&#13;
(cholesterol and triglyceride in kidney homogenate) and % change in body weight were evaluated&#13;
along with histopathological study. In present study diabetic animals treated with TG showed&#13;
significant reduction in the elevated level of plasma glucose (p&lt;0.01) when compared with diabetic&#13;
control. While considering renal parameters, diabetic animals treated with TG showed significant&#13;
decrease in serum creatinine (p&lt;0.05), urine albumin and urine total protein levels (p&lt;0.01) and&#13;
significant increase in serum albumin, total protein and % change in body weight (p&lt;0.01) when&#13;
compared with diabetic control. Diabetic control showed significant increase in total cholesterol and&#13;
triglyceride accumulation in kidney, while diabetic animals treated with TG showed significant&#13;
decrease in levels of total cholesterol (p&lt;0.01) and triglyceride (p&lt;0.05) in the kidney when compared&#13;
with diabetic control. Diabetic control showed significant mark of glomerulosclerosis and&#13;
hyalinization which occurs because of severe diabetic condition (diabetic nephropathy). Diabetic&#13;
groups treated with TG showed absence of the sclerotic lesions produced by diabetic condition. Hence,&#13;
the results obtained in the present study indicate that Tectona grandis has the potential to treat diabetes&#13;
mellitus and prevent the associated renal damage.
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