@misc{10481/99861, year = {2011}, month = {7}, url = {https://hdl.handle.net/10481/99861}, abstract = {Objective: The aim of this work is to present a longitudinal study of the refractory properties of the population of neurons involved in the generation of the evoked compound action potential (ECAP). Materials and Methods: The refractory properties of 12 subjects implanted with the Med-El Pulsar CI100 cochlear implant system have been examined by recording and analyzing ECAP responses collected under the masker-probe paradigm. Results: Our preliminary results show a statistically significant decrease of the refractory period and a statistically significant increment of the amplitudes of the ECAP responses after 3 months of cochlear implant experience. Conclusion: The evolution of the parameters describing ECAP responses reveals a decrease of the refractory period and an increment of the amplitudes associated to the use of the cochlear implant system. These changes take place in the first 3 months after the first switch-on of the cochlear implant processor and after this time the refractory period and the amplitudes tend to be stable.}, organization = {TEC2009-14245 project grant, funded by the Spanish MICINN}, organization = {AP2009-3150 fellowship, funded by the Spanish Ministry of Science, Education and Culture}, publisher = {The Journal of International Advanced Otology, AVES}, title = {Changes over time of the refractory properties measured from ECAP in Pulsa CI100 cochlear implant recipients}, author = {Ruiz Álvarez, Isaac Manuel and Torre Vega, Ángel De La and Valderrama Valenzuela, Joaquín Tomás and Roldán, Cristina and Sainz Quevedo, Manuel and Segura Luna, José Carlos and Vargas, Jose L}, }