@misc{10481/99624,
year = {2010},
url = {https://hdl.handle.net/10481/99624},
abstract = {Participation in external quality control (EQC) programmes is recommended by various scientific societies. Results from an EQC programme for embryology laboratories are presented. This 5-year programme consisted of the annual delivery of (i) materials to test toxicity and (ii) a DVD/CD-ROM with images of zygotes and embryos on days 2 and 3, on the basis of which the participants were asked to judge the embryo quality and to take a clinical decision. A high degree of agreement was considered achieved when over 75% of the laboratories produced similar classifications. With respect to the materials analysed, the specificity was 68% and the sensitivity was 83%. Concerning embryo classification, the proportion of embryos on which a high degree of agreement was achieved increased during this period from 35% to 55%. No improvement was observed in the degree of agreement on the clinical decision to be taken. Day-3 embryos produced a higher degree of agreement (58%) than did day-2 embryos (32%) (P<0.05). Participation in EQC increased the degree of inter-laboratory agreement on embryo classification, but not the corresponding agreement on clinical decision taking. It is necessary to introduce measures aimed at standardizing decision taking procedures in embryology laboratories.},
publisher = {Elsevier},
keywords = {embryology},
keywords = {embryo quality},
keywords = {quality control},
title = {External quality control for embryology laboratories},
doi = {10.1016/j.rbmo.2009.09.033},
author = {De Assin, R and Gonzalvo, MC and Clavero, A and Ramirez, JP and Vergara, F and Martinez, L and Castilla Alcalá, José Antonio},
}