@misc{10481/98965, year = {2020}, url = {https://hdl.handle.net/10481/98965}, abstract = {Abstract Importance: Intraocular pressure (IOP) is sensitive to caffeine intake and physical exercise. However, the combined effect of caffeine intake and physical exercise on IOP levels remains unknown. Background: We aimed to assess the effects of caffeine consumption before exercise on the IOP behaviour during low-intensity endurance exercise. Design: A placebo-controlled, double-blind, balanced crossover study at the University of Granada. Participants: Eighteen physically active young adults (age = 23.3 ± 2.4 years) participated in this study. Methods: Participants performed 30 minutes of cycling at 10% of maximal power production after 30 minutes of ingesting a capsule of caffeine (~4 mg/kg) and placebo in two different days and following a double-blind procedure. Main Outcome Measure: IOP was measured at baseline (before caffeine/placebo ingestion), after 5 minutes of warm-up, during cycling (6, 12, 18, 24 and 30 minutes) and recovery (5 and 10 minutes) by rebound tonometry. Results: There was a significant effect of caffeine consumption (P < .001, η2 = 0.50), showing that the ingestion of caffeine before exercise counteracted the IOP-lowering response to low-intensity endurance exercise. Greater IOP values at 12, 18, 24 and 30 minutes (corrected P-values<.05, ds = 0.90-1.08) of cycling were observed for the caffeine in comparison to the placebo condition. Conclusions and Relevance: The ingestion of caffeine (~4 mg/kg) 30 minutes before performing low-intensity endurance exercise counteracts the IOP-lowering effect of low-intensity exercise. These results highlight that the ingestion of a considerable amount of caffeine before exercise should be discouraged for individuals who would benefit from the IOP reduction associated with low-intensity exercise (ie, glaucoma patients or those at risk).}, organization = {Grupo de investigación de Óptica FQM-151}, publisher = {Wiley}, keywords = {caffeine}, keywords = {glaucoma management}, keywords = {glaucoma prevention}, keywords = {ocular hypertension}, keywords = {physical exercise}, keywords = {rebound tonometry}, title = {Effects of caffeine consumption on intraocular pressure during low‐intensity endurance exercise: A placebo‐controlled, double‐blind, balanced crossover study.}, author = {Vera Vílchez, Jesús and Redondo Cabrera, Beatriz and Bardón, Anabel and Pérez Castilla, Alejandro and García Ramos, Amador and Jiménez Rodríguez, Raimundo}, }