@misc{10481/97473,
year = {2024},
month = {11},
url = {https://hdl.handle.net/10481/97473},
abstract = {Organic Thermally Activated Delayed Fluorescence (TADF) molecules are luminescent
compounds capable of harvesting energy from triplet states without
using heavy metals. This process results in oxygen-sensitive, long-lived delayed
emission, suitable for developing optical probes for time-gated cell imaging,
oxygen sensors, and singlet oxygen photosensitizers. Despite their potential,
the use of TADF emitters in these applications is hindered by poor performance
in polar media and the challenge of balancing high photoluminescence quantum
yields, long emission lifetimes, and high triplet formation quantum yields.
In this study, novel TADF emitters are developed based on 1,8-naphthalimide
(NI) dyes, and how encapsulation in polymeric nanoparticles can enhance their
performance in aqueous media is demonstrated. The resulting nanomaterials
exhibit high delayed-to-prompt emission ratios, long delayed fluorescence
lifetimes, and exceptional applicability in time-resolved imaging. The singlet
oxygen photosensitization capabilities of the TADF nanomaterials in the photodegradation
of phenol, exploring a Förster Resonance Energy Transfer (FRET)
system that improved the efficiency, are also assessed. These findings highlight
the promising potential of TADF nanomaterials for diverse applications,
including photodegradation of pollutants, cellular imaging, and biosensing.},
organization = {University of Aveiro, Universidade NOVA de
Lisboa, Instituto Superior Técnico, FCT/MCTES, IBB},
organization = {LAQVREQUIMTE
(LA/P/0008/2020, DOI 10.54499/LA/P/0008/2020;
LA/P/0140/2020 DOI 10.54499/ LA/P/0140/2020; UIDP/04565/2020
DOI 10.54499/UIDP/04565/2020; UIDB/04565/2020 DOI
10.54499/UIDB/04565/2020; UIDP/50006/2020, DOI
10.54499/UIDP/50006/2020; and UIDB/50006/2020, DOI
10.54499/UIDB/50006/2020; PTDC/QUI-QFI/32007/2017)},
organization = {Institute of Biomedicine – iBiMED (UIDB/04501/2020},
organization = {UIDP/04501/2020) supported through national funds},
organization = {FEDER (European Fund for Regional
Development) within the PT2020 Partnership Agreement, and
Compete 2020},
organization = {doctoral grant
SFRH/BD/150 676/2020 (DOI 10.54499/SFRH/BD/150 676/2020)},
organization = {Post-doctoral grant SFRH/BPD/120 599/2016
(DOI 10.54499/SFRH/BPD/120 599/2016)},
organization = {Assistant
Researcher contract 2022.01003.CEECIND (DOI
10.54499/2022.01003.CEECIND/CP1725/CT0005)},
organization = {Grant PID2020–114256RB-I00 funded by
AEI/10.13039/501 100 011 033},
publisher = {Wiley Online Library},
keywords = {1,8-naphthalimide dyes},
keywords = {luminescent nanomaterials},
keywords = {microscopy imaging},
title = {TADF-Emitting Nanoparticles for Application as Probes in Time-Resolved Imaging and 1O2 Photosensitizers},
doi = {10.1002/adom.202402063},
author = {Diniz, Ana Marta and I. C. Crucho, Carina and Ruedas-Rama, Maria Jose and Orte Gutiérrez, Ángel and J. Dias, Cristina and Outis, Mani and N. Pinto, Sandra and F. Faustino, M. Amparo and Berberan-Santos, Mário Nuno and Avó, João},
}