@misc{10481/96660,
year = {2024},
month = {10},
url = {https://hdl.handle.net/10481/96660},
abstract = {Hypobaric hypoxia (HH) limits oxygen supply to tissues and increases metabolic demands,
especially during exercise. We studied the influence of HH exposure on the subcutaneous
adipose tissue (SAT) thickness and circulating metabolic-related cytokines levels after a resistance
training (RT) program. Twenty trained men participated in a traditional hypertrophy RT for
8 weeks (three sessions/week) under intermittent terrestrial HH (2320 m) or normoxia (N, 690 m)
conditions. Before, at week 6, and after the RT, SAT, and vastus lateralis (VL) muscle thickness
were measured by ultrasound. Blood samples were taken to analyse serum cytokines (IL-6, IL-15,
irisin, and myostatin) by multiplex immunoassay. Our findings revealed a moderate reduction in
IL-6 and irisin in HH following the RT (ES < −0.64; p < 0.05). Additionally, RT in HH promoted
serum IL-15 release (ES = 0.890; p = 0.062), which exhibited a trivial inverse association with the
reductions observed on SAT (−17.69%; p < 0.001) compared with N. RT in HH explained ~50% of
SAT variance (p < 0.001). These results highlight the benefit of stressor factors linked to RT in HH
on SAT through the modulation of serum metabolic cytokine profiles, suggesting a potential effect
on overall body composition.},
organization = {SpanishMinistry of Science, Innovation and Universities
[grant number PGC2018-097388-B-I00-MCI/AEI/FEDER, UE]},
organization = {FEDER/Junta de Andalucía-
Ministry of Economic Transformation, Industry, Knowledge, and Universities [grant number
B-CTS-374-UGR20]},
publisher = {MDPI},
keywords = {altitude},
keywords = {resistance training},
keywords = {metabolism},
title = {Exploring the Impact of Resistance Training at Moderate Altitude on Metabolic Cytokines in Humans: Implications for Adipose Tissue Dynamics},
doi = {10.3390/ijms252111418},
author = {Pérez Regalado, Sergio and León, Josefa and Padial Puche, Paulino and Benavente Bardera, Cristina and De Sousa Fernandes Alcobia de Almeida, Filipa and Bonitch-Góngora, Juan and de la Fuente, Blanca and Feriche Fernández-Castanys, María Belén},
}