@misc{10481/96507, year = {2023}, month = {3}, url = {https://hdl.handle.net/10481/96507}, abstract = {The effect of granulometric fractionation and micronization of olive pomace (OP) on the biotransformation of phenolic compounds by intestinal microbiota was investigated in vitro. Three types of powdered OP samples were incubated with human feces to simulate colonic fermentation, after a sequential static digestion: non-fractionated OP (NF), granulometrically fractionated OP (GF) and granulometrically fractionated and micronized OP (GFM). GF and GFM favored the release of hydroxytyrosol, oleuropein aglycone, apigenin and phenolic acid metabolites in the first hours of colonic fermentation compared to NF (up to 41-fold higher). GFM caused higher release of hydroxytyrosol than GF. GFM was the only sample to release tyrosol and sustained tyrosol levels up to 24 h of fermentation. Micronization associated with granulometric fractionation was more efficient than granulometric fractionation alone to increase the release of phenolic compounds from the OP matrix during simulated colonic fermentation and can be further studied for nutraceutical purposes.}, organization = {CNPq 435932/2018-7; 303654/2017-1; 422700/2021-5}, organization = {CAPES Finance code 001}, organization = {Estado do Rio Grande do Sul DCIT 41/2017}, organization = {MCIN/AEI/10.13039/501100011033}, organization = {European Union NextGenerationEU/PRTR TED2021-132489A-100}, publisher = {Elsevier}, title = {Effect of micronization on olive pomace biotransformation in the static model of colonic fermentation}, doi = {10.1016/j.foodchem.2023.135921}, author = {Sant’Anna Monteiro, Camila and Colpo Bortolazzo, Paula and Amorim Bonini, Camila Araujo and Tamires Dluzniewski, Luana and Trivisiol da Silva, Dariane and Baranzelli, Julia and Aline Smaniotto, Aline Smaniotto and Augusto Ballus, Cristiano and Lozano Sánchez, Jesús and Somacal, Sabrina and Emanuelli, Tatiana}, }