@misc{10481/96092,
year = {2015},
month = {2},
url = {https://hdl.handle.net/10481/96092},
abstract = {Background
The success of endodontic treatment depends largely on the control of microorganisms present in infected root canals. The aim of this study was to determine the residual antimicrobial activity of several final irrigation protocols with 7% maleic acid (MA) alone and combined with chlorhexidine (CHX), cetrimide (CTR) or both, in root canals infected with Enterococcus faecalis. Biofilms of E. faecalis were grown in uniradicular roots for 4 weeks. A total of 72 specimens were divided into 5 experimental groups according to the final irrigation regime used: Group 1: 2.5% NaOCl; Group 2: 7% MA; Group 3: 7% MA + 0.2% CTR; Group 4: 7% MA + 2% CHX; Group 5: 7% MA + 0.2% CTR + 2% CHX; and Control group: 0.9% saline solution. Twelve roots (2/group) that were instrumented and not infected served as negative or sterility controls. The proportion of ungrown samples over 60 days was evaluated using non-parametric Kaplan-Meier survival analysis. Differences among groups were tested using the log-rank test (p< 0.05).
Results
The association of MA with CHX and CHX + CTR as final irrigating solutions showed the best results, 5 and 4 samples out of 12, respectively, and without differences between them (p = 0.928), followed by 7% MA + 0.2% CTR with 7 out of 12. The 7% MA (11/12) group showed significant differences with respect to the groups in which MA was combined with CHX (p < 0.005) and CHX + CTR (p < 0.005).
Conclusion
Final irrigating solutions of 7% MA combined with 2% CHX or 2% CHX + 0.2% CTR were found to effectively improve antimicrobial root canal disinfection.},
organization = {Research Group CTS-167 of the Junta de Andalucía, Spain},
publisher = {Springer Nature},
keywords = {Cetrimide},
keywords = {Chlorhexidine},
keywords = {Enterococcus faecalis},
title = {Antimicrobial residual effects of irrigation regimens with maleic acid in infected root canals},
doi = {10.1186/s40709-015-0025-4},
author = {Ferrer Luque, Carmen María and González Castillo, Silvia and Ruiz Linares, Matilde and Arias Moliz, María Teresa and Rodríguez Archilla, Alberto and Baca García, María Pilar},
}