@misc{10481/95623,
year = {2024},
month = {6},
url = {https://hdl.handle.net/10481/95623},
abstract = {This article reviews the evidence for the use of different strains of probiotics in the prevention of prevalent pathologies in premature neonates.
A systematic review was conducted of the use of probiotics in neonates with less than 37 weeks of gestational age, based on a search for
systematic reviews and observational and experimental studies performed during the period from January 2014 to February 2021. For this
purpose, the PubMed, MEDLINE and Cochrane Library databases were consulted. The aim of this article was to review the existing data on the
relationship between the administration of probiotics (with different strains and doses) and the risk of necrotising enterocolitis, mortality, late
sepsis and other disease parameters in premature infants.
The literature search obtained 240 articles, of which we selected 16, representing a total sample of over 200,000 premature infants. Analysis
of the data obtained reveals statistical evidence that the combined administration of probiotics (especially of Lactobacillus and Bifidobacterium
strains) reduces the incidence of grade II or higher necrotising enterocolitis, all-cause mortality, late sepsis, length of hospital stay and time until
complete enteral nutrition is achieved. However, no benefits were apparent with respect to alleviating bronchopulmonary dysplasia, retinopathy
of prematurity or intraventricular haemorrhage.
Further research is needed to determine the most appropriate strains, doses and treatment duration for preterm infants to achieve the health
benefits identified.},
organization = {Instituto de Salud Carlos III (ISCIII) through the project
PI22/00661},
organization = {"Analysis of the functional connectivity of the brain, its morphometry and psychomotor
development of premature babies of school age: Relationship with the early nutritional contribution
received", and co-funded by the European Union},
publisher = {Arán ediciones},
keywords = {Probiotics},
keywords = {Premature infants},
keywords = {Low birth weight infants},
title = {Evidence on the benefits of probiotics for preterm infants},
doi = {10.20960/nh.03743},
author = {Campos Martínez, Ana María and Fernández-Marín, Carmen Elisabeth and Ruiz-López, Aida and Cubero Millán, Isabel and Uberos Fernández, José},
}