@misc{10481/95058,
year = {2017},
month = {1},
url = {https://hdl.handle.net/10481/95058},
abstract = {The association of occupational exposure to current-use pesticides with reproductive hormones, semen quality, and genital measures was investigated among young men in the South of Brazil. A cross-sectional study was conducted in 99 rural and 36 urban men aged 18–23 years. Information on pesticide use was obtained through questionnaire. Serum and semen samples were analyzed for sex hormones and sperm parameters, respectively, and measurement of anogenital distance (AGD) and testis volume (TV) were performed. Associations were explored using multivariate linear regression. Rural men had poorer sperm morphology, higher sperm count, and lower LH levels relative to urban subjects. Lifetime use of pesticides, especially herbicides and fungicides, was associated with poorer morphology and reduced LH and prolactin, with evidence of a linear pattern. Maternal farming during pregnancy was associated with larger AGD and TV. Chronic occupational exposure to modern pesticides may affect reproductive outcomes in young men.},
organization = {Ministry of Health, the Brazilian National Research Council (CNPq)},
organization = {CAPES (“Coordenação de Aperfeiçoamento de Pessoal de Nível Superior”)},
organization = {CNPq (“Bolsa de Produtividade em Pesquisa”)},
organization = {Science Without Borders Program A022_2013},
publisher = {Elsevier},
keywords = {Pesticides},
keywords = {Fungicides},
keywords = {Herbicides},
keywords = {Reproductive hormones},
keywords = {Sperm quality},
keywords = {Anogenital distance},
keywords = {Agricultural workers},
title = {Occupational exposure to pesticides, reproductive hormone levels and sperm quality in young Brazilian men},
doi = {10.1016/j.reprotox.2017.01.001},
author = {Cremonese, Cleber and Piccoli, Camila and Pasqualotto, Fabio and Clapauch, Ruth and Koifman, Rosalina J. and Koifman, Sergio and Freire, Carmen},
}