@misc{10481/94134, year = {2023}, month = {3}, url = {https://hdl.handle.net/10481/94134}, abstract = {Purpose: to assess and compare the changes produced by the two most commonly used substances, alcohol and cannabis, on accommodation dynamics. Methods: A total of 38 young participants (19 females) were enrolled in the study. They were assigned to two groups: a cannabis group (N = 19) and an alcohol group. Participants in the cannabis group underwent two randomized sessions: a baseline session and a session after smoking a cigarette. Participants in the alcohol group underwent three randomized sessions: a baseline session, a session after the intake of 300 ml of red wine (Alcohol 1), and other after the ingestion of 450 ml of wine (Alcohol 2). For the accommodation assessment, the open-field autorefractor WAM-5500 was used. Results: The decrease of the mean velocity of the accommodative response produced by Alcohol 2 condition was significantly greater than that observed for Alcohol 1 and Cannabis (p = 0.046). The direction of the accommodation (near-distance and distance-near) had no effect on the deterioration of the accommodation dynamics following substance use. The target distance had a significant effect on the decrease of the mean velocity following substance use (p = 0.002). The decrease of the amplitude of the accommodative response was associated with a decrease of the peak velocity (p = 0.004) and the increase of the accommodative lag (p < 0.001). Conclusions: a moderate-high dose of alcohol impairs accommodation dynamics to a greater extent that lower dose of alcohol or smoked cannabis. The deterioration of the accommodation mean speed was higher for a shorter target distance.}, organization = {Proyecto PID2020-115184RB-I00, financiado por Agencia Estatal de Investigación, MCIN/ AEI/10.13039/501100011033}, organization = {Proyecto A-FQM-532-UGR20, financiado por FEDER/Junta de Andalucía-Consejería de Transformación Económica, Industria, Conocimiento y Universidades.}, publisher = {Springer}, keywords = {Accommodation dynamics}, keywords = {Accommodative lag}, keywords = {Accommodative response}, keywords = {Alcohol consumption}, keywords = {Cannabis use}, title = {Comparison of the influence of alcohol and cannabis on the dynamics of the accommodative response}, doi = {10.1007/s00417-023-06020-5}, author = {Casares López, Miriam and Ortiz Peregrina, Sonia and Ortiz Herrera, Carolina and Castro Torres, José Juan and González Anera, Rosario}, }